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TranscriptomicsArabidopsis plants exposed to combined heat and drought stress
One of the eminent opportunities afforded by modern genomic technologies is the potential to provide a mechanistic understanding of the processes by which genetic change translates to phenotypic variation and the resultant appearance of distinct physiological traits. Indeed much progress has been m...
ORGANISM(S): Arabidopsis thaliana 
2010-05-26 | E-GEOD-9415 | biostudies-arrayexpress
TranscriptomicsMicroarray evidence for off target effects and the optimisation of targeted RNAi mediated gene silencing in the cattle tick Rhipicephalus (Boophilus) microplus
The NimbleGen cattle tick custom microarray based on the BmiGI.V2 database of R. microplus ESTs was used to screen the resulting mRNA harvested from ticks treated with the tick Ubiquitin-63E 600bp dsRNA in comparison to controls. A total of 144 ESTs including TC6372 (Ubiquitin-63E) were down-regulat...
ORGANISM(S): Rhipicephalus microplus 
2011-07-30 | E-GEOD-27453 | biostudies-arrayexpress
GenomicsHeterogeneous effects of massive hypoxia pathway activation in kidney cancer
General activation of hypoxia-inducible factor (HIF) pathways is classically associated with adverse prognosis in cancer and has been proposed to contribute to oncogenic drive. In clear cell renal carcinoma (CCRC) HIF pathways are upregulated by inactivation of the von-Hippel-Lindau tumour suppresso...
ORGANISM(S): Homo sapiens 
2015-07-10 | E-GEOD-67237 | biostudies-arrayexpress
TranscriptomicsIdentifying Sites Bound by Epstein Barr Nuclear Antigen 1 (EBNA1) in the Human Genome
Epstein-Barr virus (EBV) is a ubiquitous gammaherpes virus that establishes a life-long latency in over 90% of the world's population. Epstein Barr Nuclear Antigen 1, EBNA1, is the only viral protein consistently detected in all viral latency programs, as well as in all forms of EBV-associated malig...
ORGANISM(S): Homo sapiens 
2010-05-14 | E-GEOD-13315 | biostudies-arrayexpress
TranscriptomicsComparative Genomics of D. ethenogenes 195 and an Unsequenced Dehalococcoides-Containing Enrichment Culture
Tetrachloroethene (PCE) and trichloroethene (TCE) are prevalent groundwater contaminants that can be completely reductively dehalogenated by Dehalococcoides organisms. A Dehalococcoides-containing microbial consortium (ANAS) with the ability to degrade TCE to ethene, an innocuous end-product, was pr...
ORGANISM(S): Dehalobacter restrictus 
2010-06-20 | E-GEOD-9612 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of the transcriptome from Sulfur Deprivation Chlamydomonas cells
The Chlamydomonas reinhardtii transcriptome was characterized from nutrient-replete and sulfur-depleted wild-type and snrk2.1 mutant cells; the mutant is null for the regulatory serine-threonine kinase SNRK2.1, which is required for acclimation to sulfur deprivation. The transcriptome analyses invol...
ORGANISM(S): Chlamydomonas reinhardtii 
2010-07-07 | E-GEOD-17970 | biostudies-arrayexpress
TranscriptomicsTranscriptome of the maturing erythroblast
Understanding the pattern of gene expression and identifying the specific genes expressed during erythropoiesis is crucial for a synthesis of erythroid developmental biology. Here we have isolated four distinct populations of erythroblasts at successive erythropoietin-dependent stages of erythropoie...
ORGANISM(S): Homo sapiens 
2011-03-02 | E-GEOD-22552 | biostudies-arrayexpress
TranscriptomicscDNA Microarray 1: Compression Xylem vs. Opposite Xylem
The within-tree variation in wood properties constitutes an exceptional model to study the mechanisms that adjust the different biosynthetic pathways providing substrates with the massive and variable demands of different biosynthetic reactions of cell wall polymers. Although a few genes have been r...
ORGANISM(S): Pinus pinaster 
2012-05-05 | E-GEOD-37678 | biostudies-arrayexpress
TranscriptomicscDNA Microarray 2: Compression Xylem vs. Opposite Xylem
The within-tree variation in wood properties constitutes an exceptional model to study the mechanisms that adjust the different biosynthetic pathways providing substrates with the massive and variable demands of different biosynthetic reactions of cell wall polymers. Although a few genes have been r...
ORGANISM(S): Pinus pinaster 
2012-05-05 | E-GEOD-37736 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human serum starvation cell lines for 24hrs, 4 cell types - TERV, TERV-ST, TERV-ST110, TERV-ASB56
Study the effects of serum starvation for 24hrs on 4 cell types - TERV, TERV-ST, TERV-ST110, TERV-ASB56.
ORGANISM(S): Homo sapiens 
2004-10-01 | E-MEXP-156 | biostudies-arrayexpress
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