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TranscriptomicsMolecular Signatures of Neurogenesis in the Hippocampal Subgranular Zone of Rodents
We sought to find molecular signatures of the SGZ cell types, and to characterize the molecular pathways and transcription factor cascades that define the neurogenic niche. We used laser capture microdissection and DNA microarrays to profile gene expression in the inner (SGZ) and outer portions of t...
ORGANISM(S): Mus musculus 
2013-12-04 | E-GEOD-39697 | biostudies-arrayexpress
TranscriptomicsIntegrative Molecular Concepts Modeling of Prostate Cancer Progression
Using laser capture microdissection to isolate over 100 specific cell populations, we report the profiling of prostate cancer progression from benign epithelium to metastatic disease. By analyzing these expression signatures in the context of over 15,000 â??molecular conceptsâ??, or sets of biologic...
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-6099 | biostudies-arrayexpress
TranscriptomicsLiver tumor/normal pairs
A major challenge to the study of tumor DNA copy number (CN) in clinical specimens is the lack of appropriate fresh frozen samples and thus a dependence on Formalin-Fixed Paraffin Embedded (FFPE) banked samples, which typically have more extensive clinical follow up information. However, on most hi...
ORGANISM(S): Homo sapiens 
2009-01-22 | E-GEOD-14353 | biostudies-arrayexpress
TranscriptomicsMicroarray-based molecular subtyping of breast cancer
The primary goal of this study is to identify molecular subtypes of breast cancer through gene expression profiles of 327 breast cancer samples and determine molecular and clinical characteristics of different breast cancer subtypes. We studied expression signatures of different cellular functions (...
ORGANISM(S): Homo sapiens 
2011-04-24 | E-GEOD-20685 | biostudies-arrayexpress
TranscriptomicsFFPE study using MIP copy number platform - breast cancer I
A major challenge to the study of tumor DNA copy number (CN) in clinical specimens is the lack of appropriate fresh frozen samples and thus a dependence on Formalin-Fixed Paraffin Embedded (FFPE) banked samples, which typically have more extensive clinical follow up information. However, on most hig...
ORGANISM(S): Homo sapiens 
2010-05-05 | E-GEOD-14743 | biostudies-arrayexpress
TranscriptomicsFFPE study using MIP copy number platform - breast cancer II
A major challenge to the study of tumor DNA copy number (CN) in clinical specimens is the lack of appropriate fresh frozen samples and thus a dependence on Formalin-Fixed Paraffin Embedded (FFPE) banked samples, which typically have more extensive clinical follow up information. However, on most hig...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-14744 | biostudies-arrayexpress
TranscriptomicsFFPE study using MIP copy number platform - kidney
A major challenge to the study of tumor DNA copy number (CN) in clinical specimens is the lack of appropriate fresh frozen samples and thus a dependence on Formalin-Fixed Paraffin Embedded (FFPE) banked samples, which typically have more extensive clinical follow up information. However, on most hig...
ORGANISM(S): Homo sapiens 
2010-05-05 | E-GEOD-14740 | biostudies-arrayexpress
TranscriptomicsFFPE study using MIP copy number platform - colorectal
A major challenge to the study of tumor DNA copy number (CN) in clinical specimens is the lack of appropriate fresh frozen samples and thus a dependence on Formalin-Fixed Paraffin Embedded (FFPE) banked samples, which typically have more extensive clinical follow up information. However, on most hig...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-14742 | biostudies-arrayexpress
TranscriptomicsFFPE study using MIP copy number platform - liver
: A major challenge to the study of tumor DNA copy number (CN) in clinical specimens is the lack of appropriate fresh frozen samples and thus a dependence on Formalin-Fixed Paraffin Embedded (FFPE) banked samples, which typically have more extensive clinical follow up information. However, o...
ORGANISM(S): Homo sapiens 
2010-05-05 | E-GEOD-14745 | biostudies-arrayexpress
TranscriptomicsFFPE study using MIP copy number platform - bladder/colorectal/kidney/liver
A major challenge to the study of tumor DNA copy number (CN) in clinical specimens is the lack of appropriate fresh frozen samples and thus a dependence on Formalin-Fixed Paraffin Embedded (FFPE) banked samples, which typically have more extensive clinical follow up information. However, on most hig...
ORGANISM(S): Homo sapiens 
2009-02-17 | E-GEOD-14741 | biostudies-arrayexpress
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