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TranscriptomicsRegulation of gene expression in human T lymphoblastic leukemia Molt4 cells by farnesol
Gene expression profiles of Molt4 cells treated with DMCS (vehicle) or farnesol were compared to understand the mechanism by which farnesol induces apoptosis in these cells. Molt4 cells were treated with 75 uM farnesol for 4 hrs to compare with vehicle-treated Molt4 cells. RNA from three replicates ...
ORGANISM(S): Homo sapiens 
2014-05-01 | E-GEOD-46670 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of MOLT4 human T-ALL cells in response to miR-22-3p overexpression
MicroRNAs can play important roles in gene regulation affecting both normal development and diseases, including cancer. This microarray experiment was performed to identify genes and pathways differentially expressed in MOLT4 T-leukemia cells engineered to overexpress hsa-pre-miR-22-3p. MOLT4 cells...
ORGANISM(S): Homo sapiens 
2020-07-30 | E-MTAB-9280 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human MOLT4 cells after NFkB inactivation
MOLT4 cells in log phase (1x106 cells/ml) were pre-treated for 2 hours with the I?B? phosphorylation inhibitor BAY 11-7082 (Calbiochem) at 5?M, and the control samples with corresponding volume of DMSO. Cells were then irradiated with 4 Gy at room temperature, at a dose rate of 2.45 Gy/minute with a...
ORGANISM(S): Homo sapiens 
2009-06-30 | E-MEXP-2177 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human irradiated MOLT4 cells to measure measure of degradation rates by actinomycin D
MOLT4 cells in log phase (1x106 cells/ml) were irradiated with 4 Gy at room temperature, at a dose rate of 2.45 Gy/minute with a 137Cs ?-irradiator. After 4 hours, actinomycin D (5 ?M) was added to block transcription. Aliquots of culture were removed at hourly intervals and RNA was extracted (Triz...
ORGANISM(S): Homo sapiens 
2009-06-30 | E-MEXP-2179 | biostudies-arrayexpress
GenomicsRNA sequencing of K562 and MOLT4 cell lines
RNA sequencing of K562 and MOLT4 cell lines
PRJNA624306 | ENA
TranscriptomicsExpression data from MOLT4 human cell line
To compare The pattern of Gene expression by 7-hydroxymethotrexate-resistant human leukemia cells reveals changes designed to preserve intracellular levels of folate and nucleotide biosynthesis We used microarrays to detail the global programme of gene expression underlying cellularisation and ident...
ORGANISM(S): Homo sapiens 
2006-06-22 | GSE5118 | GEO
TranscriptomicsRegulation of gene expression in human T lymphoblastic leukemia Molt4 cells by farnesol
Gene expression profiles of Molt4 cells treated with DMCS (vehicle) or farnesol were compared to understand the mechanism by which farnesol induces apoptosis in these cells.
ORGANISM(S): Homo sapiens 
2014-05-01 | GSE46670 | GEO
TranscriptomicsRNA sequencing of K562 and MOLT4 cell lines
Here, we present global microprotein quantitation in two human leukemia cell lines, K562 and MOLT4. We identify unannotated microproteins that are differentially expressed in these cell lines. The expression of six microproteins was validated biochemically, and two were found to localize to the nucl...
ORGANISM(S): Homo sapiens 
2020-06-03 | GSE148451 | GEO
TranscriptomicsChromatin immunoprecipitation of human and chimp cell lines GM06990, HFL1, HeLaS3, MOLT4 and PTR8 with anti Histone H3K4me1, H3K4me2, H3K4me3, H3ac and H4ac antibodies using an ENCODE array
ENCODE ChIP/chip study using human lymphoblastoid cell line GM06990; human cervix carcinoma cell line HeLaS3; human fetal lung fibroblast cell line HFL1; human T cell line MOLT4; chimpanzee lymphoblastoid cell line PTR8; and anti Histone H3K4me1 (Abcam; ab8895); H3K4me2 (Abcam; ab7766); H3K4me3 (Abc...
ORGANISM(S): Pan troglodytes 
2006-08-30 | E-TABM-138 | biostudies-arrayexpress
TranscriptomicsSingle-cell transcriptomic analysis of SP11-treated MOLT4 cell line and untreated control.
We used single-cell RNA sequencing with the 10x Genomics platform to study the effect of SP11 treatment in a MOLT4. The goal was to examine tumor heterogeneity, identify potential treatment-resistant cell populations, and assess changes in the intercellular communication. This dataset provides an ov...
ORGANISM(S): Homo sapiens 
2026-07-01 | GSE328525 | GEO
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