Monoubiquitination

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Co-dependency of H2B monoubiquitination and nucleosome re-assembly on Chd1

Monoubiquitination of histone H2B on lysine 123 (H2BK123ub) is a transient histone modification considered to be essential for establishing H3K4 and H3K79 trimethylation by Set1/COMPASS and Dot1, respectively. Many of the factors such as Rad6/Bre1, the Paf1 complex, and the Bur1/Bur2 complex were ...

ORGANISM(S): Saccharomyces cerevisiae

2012-05-01 | E-GEOD-36334 | biostudies-arrayexpress

GlcNAcylation of histone H2B facilitates its monoubiquitination [Illumina Genome Analyzer data]

We report that histone GlcNAcylation of H2B S112 is a vital histone modification which facilitates histone monoubiquitination (ub). In a genome-wide analysis, H2B S112 GlcNAcylation sites were observed widely distributed over entire chromosomes including transcribed gene loci, together with co-local...

ORGANISM(S): Homo sapiens

2011-10-27 | E-GEOD-33049 | biostudies-arrayexpress

The Histone H2B Monoubiquitination Regulatory Pathway is Required for Differentiation of Multipotent Stem Cells

Extensive changes in post-translational histone modifications accompany the rewiring of the transcriptional program during stem cell differentiation. However, the mechanisms controlling the changes in specific chromatin modifications and their function during differentiation remain only poorly under...

ORGANISM(S): Homo sapiens

2013-01-03 | E-GEOD-38173 | biostudies-arrayexpress

Cellular Validation of Chemically Improved Inhibitor Identifies Monoubiquitination on OTUB2

Ubiquitin thioesterase OTUB2, a cysteine protease from the ovarian tumor (OTU) deubiquitinase superfamily, is associated with enhanced expression during tumor progression and metastasis. Development of OTUB2 inhibitors is therefore believed to be therapeutically important, yet potent and selective s...

ORGANISM(S): Homo sapiens (Human)

2023-06-27 | PXD041346 | Pride

GlcNAcylation of histone H2B facilitates its monoubiquitination

This SuperSeries is composed of the following subset Series: GSE33049: GlcNAcylation of histone H2B facilitates its monoubiquitination [Illumina Genome Analyzer data] GSE33050: GlcNAcylation of histone H2B facilitates its monoubiquitination [Affymetrix data] Refer to individual Series

ORGANISM(S): Homo sapiens

2011-10-26 | E-GEOD-33051 | biostudies-arrayexpress

Monoubiquitination in Homeostasis and Cancer.

Not available

S-EPMC9180643 | biostudies-literature

Essential roles of Windei and nuclear monoubiquitination of Eggless/SETDB1 in transposon silencing

PRJNA526876 | ENA

Microarray Analysis Reveals Potential Biological Functions of Histone H2B Monoubiquitination.

Not available

S-EPMC4503354 | biostudies-literature

The genetic and biochemical basis of FANCD2 monoubiquitination.

Not available