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TranscriptomicsDifferential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice.
Obesity-associated insulin resistance is characterized by a state of chronic, low-grade inflammation that is associated with the accumulation of M1 proinflammatory macrophages in adipose tissue. Although different evidence explains the mechanisms linking the expansion of adipose tissue and adipose t...
ORGANISM(S): Mus musculus 
2012-03-22 | E-GEOD-36669 | biostudies-arrayexpress
TranscriptomicsComparative analysis from hESC from different developmental sources of derivation
Whole genome expression analysis reveals that single blastomeres from day-3 human embryos and blastocysts show unique gene signature, thus hESC derived from these two developmental sources might show differential gene expression profile. Comparative gene expression analysis has revealed that no sig...
ORGANISM(S): Homo sapiens 
2012-11-27 | E-GEOD-42520 | biostudies-arrayexpress
UnknownDevelopment and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study.
Not available
S-EPMC4380415 | biostudies-literature
TranscriptomicsDifferentiation of Human Embryonic Stem Cells under Hypoxia Conditions
Early development of mammalian embryos occurs in an environment of relative hypoxia. Nevertheless, human embryonic stem cells (hESC), which are derived from the inner cell mass of blastocyst, are routinely cultured under the same atmospheric conditions (21% O2) as somatic cells. We hypothesized that...
ORGANISM(S): Homo sapiens 
2012-05-04 | E-GEOD-37761 | biostudies-arrayexpress
TranscriptomicsDifferential microRNA expression profiling between human induced pluripotent stem cells (iPSCs) and human neonatal dermal fibroblasts (NDFs).
We have employed microRNA expression profiling of iPSCs and NDFs as a discovery platform to identify microRNAs involved in reprogramming of NDFs to iPSCs. Using Agilent human miRNA (V3) 8X15K microarray, we performed microRNA profiling of iPSCs at passage 20 and NDFs at passage 5
ORGANISM(S): Homo sapiens 
2015-05-09 | E-GEOD-68672 | biostudies-arrayexpress
UnknownLoss to Follow-Up from HIV Screening to ART Initiation in Rural China.
Not available
S-EPMC5074455 | biostudies-literature
TranscriptomicsTranslatome of Jurkat cells: control vs. stress treatment.
Translation efficiencies of Jurkat mRNAs in control and in cells treated with thapsigargin 10microM for 1h and 3h. Three-conditions experiments. Biological replicates: 1 from three pooled control experiments, 1 from three pooled 1h stress experiment, 1 from three pooled 3h stress experiment.
ORGANISM(S): Homo sapiens 
2012-03-02 | E-GEOD-36207 | biostudies-arrayexpress
TranscriptomicsTranslatome of NIH3T3 cells: control vs. stress treatment
Translation efficiencies of mouse mRNAs in control and in cells treated with thapsigargin 10microM for 3h. Two-conditions experiments. Biological replicates: 1 from three pooled control experiments, 1 from three pooled stress experiments
ORGANISM(S): Mus musculus 
2012-03-02 | E-GEOD-36206 | biostudies-arrayexpress
TranscriptomicsMicroarray Expression Data from Haematopoietic Differentiated Human Embryonic Stem Cells
The underlying mechanisms which are responsible and govern early haematopoietic differentiation during development are poorly understood. Gene expression comparison between pluripotent human embryonic stem cells and earliest haematopoietic progenitors may reveal novel transcripts and pathways and p...
ORGANISM(S): Homo sapiens 
2012-01-06 | E-GEOD-29115 | biostudies-arrayexpress
TranscriptomicsExpression data from Caenorhabditis elegans fed with 13L cocoa peptide
Cocoa protein content is a very interesting source for isolation of antioxidant bio-peptides, which can be used for the prevention of age-related diseases. We use microarrays to study the global genome expression of C. elegans fed with a peptide (13L) isolated from cocoa. Wild type strain N2 of C. e...
ORGANISM(S): Caenorhabditis elegans 
2013-12-31 | E-GEOD-44318 | biostudies-arrayexpress
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