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ProteomicsCRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti-tumoral compounds
FOXL2 is a transcription factor that plays a key role in sex determination, ovary development and maintenance. Mutations related to this gene have been described in syndromes involving premature ovarian failure and granulosa cell tumors. This kind of rare cancer (less than 5% of diagnosed ovarian ca...
ORGANISM(S): Homo sapiens (Human) 
2025-03-15 | PXD053682 | Pride
Tmt Rare cancer Crispr Granulosa cell tumor Proteomics Foxl2 
TranscriptomicsMicroarray of E. faecalis strain VE14089 and codY deletion strain -VE18073
Cells were grown in Brain Heart Infusion broth to an OD of 0.5, and RNA was extracted.
ORGANISM(S): Enterococcus faecalis 
2011-06-30 | E-MEXP-3068 | biostudies-arrayexpress
UnknownKnowledge about E-Cigarettes and Tobacco Harm Reduction among Public Health Residents in Europe.
Not available
S-EPMC6617304 | biostudies-literature
UnknownA Nanoencapsulated Ir(III)-Phthalocyanine Conjugate as a Promising Photodynamic Therapy Anticancer Agent.
Not available
S-EPMC11299137 | biostudies-literature
UnknownEffectiveness of an intensive E-mail based intervention in smoking cessation (TABATIC study): study protocol for a randomized controlled trial.
Not available
S-EPMC3648415 | biostudies-literature
UnknownAccuracy of a raw saliva-based COVID-19 RT-LAMP diagnostic assay.
Not available
S-EPMC10391658 | biostudies-literature
ProteomicsDynamics of the Escherichia coli proteome in response to the deletion of the Tat pathway
In Escherichia coli, the Twin-arginine (Tat) secretion system is one of the main routes of the protein export to the periplasm. The Tat pathway secretes a set of proteins with important physiological functions. In our study, we investigated the influence of the deactivation of the Tat pathway on the...
ORGANISM(S): Escherichia coli 
2019-02-18 | PXD008803 | Pride
Escherichia coli Stress responses Tat pathway 
UnknownPersistent multispecies dissemination of <i>armA</i>-carrying IncR plasmids among clinical and environmental bacterial populations in a Spanish veterinary hospital.
Not available
S-EPMC12607884 | biostudies-literature
UnknownActivity modulation of the Escherichia coli F1FO ATP synthase by a designed antimicrobial peptide via cardiolipin sequestering.
Not available
S-EPMC10320169 | biostudies-literature
UnknownRotation of the c-Ring Promotes the Curvature Sorting of Monomeric ATP Synthases.
Not available
S-EPMC10625105 | biostudies-literature
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