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ProteomicsA multidisciplinary integrated approach for the identification and characterization of the AMP profile in Hermetia illucens hemolymph
The growing threat of antimicrobial resistance calls for alternative strategies to conventional antibiotics. Insects represent a promising source of antimicrobial peptides (AMPs) due to their potent innate immune responses. In this study, we investigated the peptide extracts from hemolymph of Hermet...
ORGANISM(S): Hermetia illucens 
2026-06-01 | PXD071144 | Pride
Antimicrobial peptides  hermetia illucens  antimicrobial resistance  proteomics  in vitro antibacterial assay  in silico prediction 
ProteomicsProteomic and degradomic signatures of extracellular matrix remodeling in calcific aortic valve stenotic
Calcific aortic valve disease (CAVD) is the most common valvular heart disease in older adults, but no medical therapy is currently able to halt or reverse its progression, partly because the molecular mechanisms of valve remodeling remain incompletely understood. Here, we aimed to dissect the extra...
ORGANISM(S): Homo sapiens (Human) 
2026-05-29 | PXD070758 | Pride
Calcific aortic valve disease Collagen post-translational modifications Aortic valve stenosis Extracellular matrix remodeling proteomics 
ProteomicsProteomic and degradomic signatures of extracellular matrix remodeling in calcific aortic valve
Calcific aortic valve disease (CAVD) is the most common valvular heart disease in older adults, but no medical therapy is currently able to halt or reverse its progression, partly because the molecular mechanisms of valve remodeling remain incompletely understood. Here, we aimed to dissect the extra...
ORGANISM(S): Homo sapiens (Human) 
2026-05-29 | PXD073246 | Pride
Aortic valve stenosis Extracellular matrix remodeling proteomics Calcific aortic valve disease Collagen post-translational modifications 
ProteomicsIntegrating Proteomics and Bioinformatics Methods for the Identification of Breast Cancer Biomarkers Interacting with Telomeric G-Quadruplex
The identification of reliable biomarkers is imperative for enhancing early detection, prognosis, and treatment of breast cancer. This study investigates a human telomeric dimeric G-quadruplex (G4) model, Tel46, which has been functionalized on Controlled Pore Glass (CPG) support, as a novel tool fo...
ORGANISM(S): Homo sapiens (Human) 
2025-09-15 | PXD059597 | Pride
Bioinformatics Telomeric g-quadruplex Proteomics Dna-protein interactions. Breast cancer biomarkers 
ProteomicsIntegrating Proteomics and Bioinformatics Methods for the Identification of Breast Cancer Biomarkers Interacting with Telomeric G-Quadruplex
The identification of reliable biomarkers is imperative for enhancing early detection, prognosis, and treatment of breast cancer. This study investigates a human telomeric dimeric G-quadruplex (G4) model, Tel46, which has been functionalized on Controlled Pore Glass (CPG) support, as a novel tool fo...
ORGANISM(S): Homo sapiens (Human) 
2025-09-15 | PXD059593 | Pride
Bioinformatics Telomeric g-quadruplex Proteomics Dna-protein interactions. Breast cancer biomarkers 
UnknownLysines Acetylome and Methylome Profiling of H3 and H4 Histones in Trichostatin A-Treated Stem Cells.
Not available
S-EPMC7921975 | biostudies-literature
UnknownOvercoming BET-inhibitor JQ1 resistance in aggressive non-small cell lung cancer by inducing ferroptosis via inhibition of the BRD2-FTH1 axis.
Not available
S-EPMC12699187 | biostudies-literature
UnknownMetformin overdose, but not lactic acidosis per se, inhibits oxygen consumption in pigs.
Not available
S-EPMC3580617 | biostudies-literature
UnknownEvaluation of a Whole-Liver Dixon-Based MRI Approach for Quantification of Liver Fat in Patients with Type 2 Diabetes Treated with Two Isocaloric Different Diets.
Not available
S-EPMC8871286 | biostudies-literature
UnknownThymic Stromal Lymphopoietin (TSLP) Is Cleaved by Human Mast Cell Tryptase and Chymase.
Not available
S-EPMC11012384 | biostudies-literature
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