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ProteomicsComparative single-cell and spatial transcriptomics illuminate bat immunity and barrier tissue evolution
Bats have adapted to pathogens through diverse mechanisms, including increased resistance - rapid pathogen elimination, and tolerance - limiting tissue damage following infection. In the Egyptian fruit bat (an important model in comparative immunology) several mechanisms conferring disease toleranc...
ORGANISM(S): Rousettus aegyptiacus (Egyptian rousette) (Egyptian fruit bat) Mus musculus (Mouse) 
2024-11-18 | PXD058003 | Pride
Proteomics Bat Immunity Lc-ms/ms 
UnknownNovel variants in PNPLA6 causing syndromic retinal dystrophy.
Not available
S-EPMC7855329 | biostudies-literature
TranscriptomicsTMEM88 knockdown during human embryonic stem cell cardiac differentiation
TMEM88 is indispensable for heart development and acts in the pre-cardiac mesoderm to specify lineage commitment of the cardiovascular progenitor cell through inhibition of Wnt signaling. 2 different lentiviruses expression shRNA targeting different domains of the TMEM88 locus were transduced into u...
ORGANISM(S): Homo sapiens 
2013-10-21 | E-GEOD-43805 | biostudies-arrayexpress
ProteomicsMultimodal cell maps as a foundation for structural and functional genomics
Human cells contain a complex hierarchy of components, many of which remain uncharted. Here we broadly identify subcellular components across the 10–9–10–5 meter range, via self-supervised fusion of immunofluorescence images and biophysical interactions measured for >5100 proteins in U2-OS human cel...
ORGANISM(S): Homo sapiens (Human) 
2025-01-08 | PXD052362 | Pride
Size-exclusion chromatography Protein-correlation profiling Lcmsms 
UnknownSensitive and reproducible detection of SARS-CoV-2 using SERS-based microdroplet sensor.
Not available
S-EPMC9121656 | biostudies-literature
UnknownBili inhibits Wnt/beta-catenin signaling by regulating the recruitment of axin to LRP6.
Not available
S-EPMC2701632 | biostudies-literature
UnknownSafety and Immunogenicity of a Tetravalent Dengue DNA Vaccine Administered with a Cationic Lipid-Based Adjuvant in a Phase 1 Clinical Trial.
Not available
S-EPMC5930886 | biostudies-literature
UnknownMicrofluidic device generating stable concentration gradients for long term cell culture: application to Wnt3a regulation of β-catenin signaling.
Not available
S-EPMC4106280 | biostudies-literature
TranscriptomicsDrosophila expression data from larval, prepupal and pupal wings to identify targets of Hox protein Ultrabithorax (Ubx)
Hox genes regionalize the animal body axis by modifying complex morphogenetic and differentiation processes during development. The transformation of wings into halteres by the Hox gene Ultrabithorax (Ubx) in Drosophila melanogaster presents an excellent model system to study the transcriptional net...
ORGANISM(S): Drosophila melanogaster 
2010-12-31 | E-GEOD-22354 | biostudies-arrayexpress
UnknownMicroenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt-β-catenin signaling.
Not available
S-EPMC3591802 | biostudies-literature
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