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Loss of expression of the cell-cell adhesion molecule E-cadherin is an essential event for epithelial-mesenchymal transition (EMT), a process that allows cell migration in the developing embryo and during tumour invasion. Transcriptional repression has emerged as the main mechanism responsible for E...
ORGANISM(S): Canis lupus familiaris 
Skeletal muscle plays a critical role in the onset and development of type II diabetes. However, very few studies have investigated the potential pathogenic role of its most abundant protein, myosin. Hence, here, we aim to define this by focusing on myosin energy-saving state known as super-relaxed ...
ORGANISM(S): Homo sapiens (Human) 
2025-04-29 | PXD053022 | Pride
B. pertussis Tohama I was grown in iron-depleted or iron-replete media and sampled at several time points to assess global gene expression
ORGANISM(S): Bordetella pertussis 
Respiratory complex I plays a crucial role in the mitochondrial electron transport chain and shows promise as a therapeutic target for various human diseases. While most studies focus on inhibiting complex I at the Q-site, little is known about inhibitors targeting other sites within the complex. In...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD047527 | Pride

Malaria-naive male rhesus macaques (Macaca mulatta), approximately four years of age, were inoculated intravenously with salivary gland sporozoites produced and isolated at the Centers for Disease Control and Prevention from multiple Anopheles species (An. dirus, An. gambi...

ORGANISM(S): Macaca Mulatta Plasmodium Cynomolgi Strain B 
2017-03-16 | MSV000080637 | MassIVE
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