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UnknownResident gut microbiota community determines the efficacy of soluble fiber in reducing adiposity.
Not available
S-EPMC11091261 | biostudies-literature
GenomicsAnalysis of Blimp-1 and Irf-1 genomic binding in wild type and Prdm1/Blimp-1 mutant embryonic gut
The goal of this study was to profile Blimp1 binding in E18.5 small intestine using a Blimp-1-eGFP knock-in allele, and to compare Blimp-1-eGFP genomic binding with Irf-1 genomic binding in normal small intestine. Changes in Irf-1 binding between wild type and Prdm1/Blimp-1 mutant small intestine w...
ORGANISM(S): Mus musculus 
2015-07-10 | E-GEOD-66069 | biostudies-arrayexpress
TranscriptomicsPhotoperiod regulates genes encoding melanocortin 3 and serotonin receptors, and secretogranins expressed in the dmpARC of the Siberian hamster
The mechanism(s) involved in the regulation of the seasonal-appropriate body weight of the Siberian hamster is currently unknown. We have identified photoperiodically regulated genes including VGF in a sub-region of the arcuate nucleus termed the dorsomedial posterior arcuate (dmpARC). Gene expressi...
ORGANISM(S): Phodopus sungorus 
2010-05-15 | E-GEOD-10278 | biostudies-arrayexpress
TranscriptomicsExpression data from F344N rats in long and short photoperiods
Rats were housed in either long day (LD, 16:8 hours, light:dark) or short day (SD, 8:16 hours, light dark) photoperiods for 3, 14 and 28 days and brains removed, frozen on dry ice and then hypothalamic arcuate nucleus tissue blocks cut for RNA extraction. At each time point 4 rats were used in each ...
ORGANISM(S): Rattus norvegicus 
2012-02-21 | E-GEOD-27926 | biostudies-arrayexpress
TranscriptomicsDiet induced obesity is independent of metabolic endotoxemia, Tlr4 signalling and hypothalamic inflammation
A number of studies have proposed that excess food intake, particularly of high fat diets arise due dysregulation of homeostatic mechanisms regulating neuroendocrine control of appetite and energy balance. Current dogma suggests high fat diets invoke hypothalamic inflammation which reduces hypothala...
ORGANISM(S): Mus musculus 
2018-10-23 | E-MTAB-6929 | biostudies-arrayexpress
UnknownOral 11β-HSD1 inhibitor AZD4017 improves wound healing and skin integrity in adults with type 2 diabetes mellitus: a pilot randomized controlled trial.
Not available
S-EPMC8942338 | biostudies-literature
UnknownStudy of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus.
Not available
S-EPMC3033530 | biostudies-literature
UnknownAssociation of CD40 with rheumatoid arthritis confirmed in a large UK case-control study.
Not available
S-EPMC3009392 | biostudies-literature
UnknownAssociation of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response.
Not available
S-EPMC4928097 | biostudies-literature
Proteomicsc-Abl Dependent Tyrosine Phosphorylation of theCo-chaperone Aha1 Regulates Interaction with Hsp90
The ability of Heat Shock Protein 90 (Hsp90) to hydrolyze ATP is essential for its chaperone function. The co-chaperone Aha1 stimulates Hsp90 ATPase activity tailoring the chaperone function to specific “client” proteins. The intracellular signaling mechanisms directly regulating Aha1 association wi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080713 | MassIVE
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