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TranscriptomicsComparative transcriptional analysis of Desulfovibrio alaskensis G20 grown under various syntrophic and fermentative conditions on pyruvate relative to respiratory growth
Pyruvate fermentation pathway and energetics of Desulfovibrio alaskensis strain G20 under syntrophic coculture and fermentative monoculture conditions Expression data for Desulfovibrio alaskensis strain G20 grown in chemostats on pyruvate under respiratory conditions (sulfate-limited and pyruvate-li...
ORGANISM(S): Desulfovibrio alaskensis G20 
2013-12-12 | E-GEOD-53226 | biostudies-arrayexpress
TranscriptomicsLinking toxicant physiological mode of action with induced gene expression changes in Caenorhabditis elegans: cadmium
Physiologically based modelling using DEBtox (dynamic energy budget in toxicology) and transcriptional profiling were used in Caenorhabditis elegans to identify how physiological modes of action, as indicated by effects on system level resource allocation were associated with changes in gene express...
ORGANISM(S): Caenorhabditis elegans 
2010-05-05 | E-GEOD-21010 | biostudies-arrayexpress
TranscriptomicsLinking toxicant physiological mode of action with induced gene expression changes in Caenorhabditis elegans: atrazine
Physiologically based modelling using DEBtox (dynamic energy budget in toxicology) and transcriptional profiling were used in Caenorhabditis elegans to identify how physiological modes of action, as indicated by effects on system level resource allocation were associated with changes in gene express...
ORGANISM(S): Caenorhabditis elegans 
2010-03-23 | E-GEOD-21008 | biostudies-arrayexpress
UnknownAssociation of the IL2RA/CD25 gene with juvenile idiopathic arthritis.
Not available
S-EPMC2963023 | biostudies-literature
TranscriptomicsLinking toxicant physiological mode of action with induced gene expression changes in Caenorhabditis elegans: fluoranthene
Physiologically based modelling using DEBtox (dynamic energy budget in toxicology) and transcriptional profiling were used in Caenorhabditis elegans to identify how physiological modes of action, as indicated by effects on system level resource allocation were associated with changes in gene express...
ORGANISM(S): Caenorhabditis elegans 
2010-05-05 | E-GEOD-21011 | biostudies-arrayexpress
GenomicsEffects of dynamic cytosine methylation on alternative pre-mRNA splicing in T lymphocytes
Intragenic 5-methylcytosine and CTCF mediate opposing affects on pre-mRNA splicing: CTCF promotes inclusion of weak upstream exons through RNA polymerase II pausing, whereas 5-methylcytosine evicts CTCF, leading to exon exclusion. However, the mechanisms governing dynamic DNA methylation at CTCF bin...
ORGANISM(S): Homo sapiens 
2016-01-04 | E-GEOD-74850 | biostudies-arrayexpress
TranscriptomicsDeciphering myeloma risk loci by eQTL analysis
Recent genome-wide association studies have identified single nucleotide polymorphisms (SNPs) at 7 loci influencing multiple myeloma (MM) risk. We generated expression quantitative trait loci (eQTL) data on malignant plasma cells from two patient series (totaling 848) to fine map the risk loci assoc...
ORGANISM(S): Homo sapiens 
2014-12-09 | E-MTAB-2299 | biostudies-arrayexpress
Genomics463 newly diagnosed patients with Multiple Myeloma underwent whole exome sequencing of tumour and peripheral blood DNA.
463 newly diagnosed patients from the UK Myeloma XI clinical trial (NCT01554852) underwent whole exome sequencing plus targeted capture of the IGH/K/L and MYC loci. 200 ng of DNA were processed using NEBNext DNA library prepartion kit and hybridised to the SureSelect Human All Exon V5 Plus. Four s...
EGAS00001001147 | EGA
TranscriptomicsGene expression profiling of rhesus macaques vaccinated with ALVAC-SIVgpe DNA + SIVgp120 protein subunit and unvaccinated controls after challenge with SIVmac251 - 3 wks post-infection
The SIVmac251 macaque model has been used to evaluate the efficacy of vaccine for HIV. Exposure of macaques to a single high dose of SIVmac251 results in transmission of multiple viral variants, which contrasts the few HIV variants typically transmitted in humans. In here, we investigated whether th...
ORGANISM(S): Macaca mulatta 
2013-03-01 | E-GEOD-37311 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of rhesus macaques vaccinated with ALVAC-SIVgpe DNA + SIVgp120 protein subunit and unvaccinated controls after challenge with SIVmac251 - 11 wks post-infection
The SIVmac251 macaque model has been used to evaluate the efficacy of vaccine for HIV. Exposure of macaques to a single high dose of SIVmac251 results in transmission of multiple viral variants, which contrasts the few HIV variants typically transmitted in humans. In here, we investigated whether th...
ORGANISM(S): Macaca mulatta 
2013-03-01 | E-GEOD-37312 | biostudies-arrayexpress
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