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Metabolic flexibility in skeletal muscle is essential for maintaining healthy glucose and lipid metabolism, and its dysfunction is closely linked to metabolic diseases. Exercise enhances metabolic flexibility, making it an important tool for discovering mechanisms that promote efficient energy metab...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-25 | PXD057017 | Pride
Pluripotency represents a cell state comprising a fine-tuned pattern of transcription factor activity required for embryonic stem cell (ESC) self-renewal. TBX3 is the earliest expressed member of the T-box transcription factor family and is involved in maintenance and induction of pluripotency. Henc...
ORGANISM(S): Mus musculus 
PBMCs of patients with AVS having TET2 mutations versus those with no known CHIP mutations were utilized for scRNA-seq
ORGANISM(S): Homo sapiens 
Neuroblastoma is a malignant pediatric tumor of the sympathetic nervous system1. Roughly half of these tumors regress spontaneously or are cured by limited therapy. By contrast, high-risk neuroblastomas have an unfavorable clinical course despite intensive multimodal treatment, and their molecular b...
Data Access Committee EGAC00001000361
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