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Metabolomicsmetabolomics Analysis in Cecal Samples
Targeted LC/MS Metabolomics. Cecal contents were lyophilized overnight and approximately 2.5-5 mg was homogenized in 250 µL of 50% acidified acetonitrile (0.3% formic acid) for targeted LC/MS/MS metabolomics (acylcarnitines, amino acids, organic acids, nucleotides, and CoAs) according to validated, ...
2026-06-19 | MTBLS14783 | MetaboLights
TranscriptomicsTranscription profiling of CEPH individuals from the International HapMap Project
Baseline expression levels of genes in CEPH individuals from the International HapMap Project were measured using the Affymetrix Human Genome Focus Arrays. Arrays were analyzed using MAS 5.0 software (Affymetrix).
ORGANISM(S): Homo sapiens 
2007-06-22 | E-GEOD-2552 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human lymphoblasts from HapMap populations CEU, CHB, JPY reveals allelic differences account for gene expression differences among populations
Expression level of genes in lymphoblasts from individuals in three HapMap populations (CEU, CHB, JPT) were compared. More than 1,000 genes were found to be significantly different (Pc<0.05) in mean expression level between the CEU and CHB+JPT samples. Experiment Overall Design: Gene expression ana...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5859 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CEPH panel members to investigate natural variation in human gene expression
We measured the baseline expression levels of genes in members of the CEPH pedigrees using Affymetrix Human Genome Focus Arrays. Arrays were analyzed using MAS 5.0 software (Affymetrix).
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-1485 | biostudies-arrayexpress
TranscriptomicsNatural variation in human gene expression assessed in lymphoblastoid cells
Lymphoblastoid cells from 35 unrelated individuals used to examined variation in gene expression. Identified genes whose transcript levels differed greatly among unrelated individuals.
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-137 | biostudies-arrayexpress
TranscriptomicsGene expression levels in immortalized B cells from members of 45 CEPH-Utah pedigrees
We used microarrays to examine gene expression levels from members of 45 CEPH-Utah pedigrees. Keywords: array-based gene expression We measured gene expression levels in immortalized B cells from members of 45 CEPH-Utah pedigrees. For some cell lines, RNA extracts were hybridized twice, representi...
ORGANISM(S): Homo sapiens 
2010-09-21 | E-GEOD-16778 | biostudies-arrayexpress
TranscriptomicsPolymorphic cis- and trans-regulation of human gene expression
Expression levels of human genes vary extensive among individuals. Gene expression determines cell function and characteristics thus this variation likely contributes to phenotypic variation. Genetic studies have shown that there is a heritable component to gene expression variation, and have iden...
ORGANISM(S): Homo sapiens 
2010-09-19 | E-GEOD-16921 | biostudies-arrayexpress
MetabolomicsBiodiversity in marine invertebrate responses to acute warming revealed by a comparative multi-omics approach
Understanding species' responses to environmental change underpins our abilities to make predictions on future biodiversity under any range of scenarios. In spite of the huge biodiversity in most ecosystems, a model species approach is often taken in environmental studies. To date, we still do not k...
2016-06-23 | MTBLS336 | MetaboLights
TranscriptomicsLong noncoding RNAs are spatially correlated with transcription factors and regulate lung development
To identify potential biological functions for three lncRNAs (NANCI, LL12, and LL34) we used shRNAs to knockdown expression of lncRNAs in MLE12 cells, a cell resembling type two lung epithelial cells. This data set contains the microarrays looking at gene expression. We used biological triplicate fo...
ORGANISM(S): Mus musculus 
2014-07-22 | E-GEOD-52389 | biostudies-arrayexpress
TranscriptomicsA mesodermal gene regulatory network directed by zebrafish No tail
Using chromatin immunoprecipitation combined with microarrays we have identified targets of No tail (Ntl), a zebrafish Brachyury ortholog that plays a central role in mesoderm formation. We show that Ntl regulates a downstream network of other transcription factors and identify an in vivo Ntl bindin...
ORGANISM(S): Danio rerio 
2009-02-19 | E-GEOD-12331 | biostudies-arrayexpress
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