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ProteomicsMeningeal γδ T cells producing IL-17 control synaptic plasticity and cognitive behaviour
The conventional notion of “immune privilege” of the brain has been revised to accommodate its infiltration, at steady state, by immune cells that participate in normal neurophysiology (Louveau, Trends Immunol 2015; Kipnis science 2016; Filiano, Nat Rev Neurosciences 2017). Surprisingly, such neuroi...
ORGANISM(S): Mus musculus (Mouse) 
2019-10-16 | PXD007574 | Pride
Swath Il-17 Γδ t cells 
UnknownPre-clinical data supporting immunotherapy for HIV using CMV-HIV-specific CAR T cells with CMV vaccine.
Not available
S-EPMC9062763 | biostudies-literature
TranscriptomicsCav3.2 T-type calcium channel-dependent gene expression after retrieval of context-associated memory (left hippocampus)
Among all voltage-gated calcium channels, the T-type Ca2+ channels encoded by the Cav3 genes are highly expressed in the hippocampus, which is associated with contextual, temporal and spatial learning and memory. However, the specific involvement of the Cav3.2 T-type Ca2+ channel in these hippocampu...
ORGANISM(S): Mus musculus 
2013-02-28 | E-GEOD-30842 | biostudies-arrayexpress
TranscriptomicsModification of T cell responses by stem cell mobilization requires direct signalling of the T cell by G-CSF and IL-10
The majority of allogeneic stem cell transplants are currently undertaken using G-CSF mobilized peripheral blood stem cells. G-CSF has diverse biological effects on a broad range of cells and IL-10 is a key regulator of many of these effects. Using mixed radiation chimeras in which the haematopoieti...
ORGANISM(S): Mus musculus 
2014-02-03 | E-GEOD-54616 | biostudies-arrayexpress
UnknownA new class of bispecific antibodies to redirect T cells for cancer immunotherapy.
Not available
S-EPMC3984327 | biostudies-literature
UnknownTC-PTP regulates the IL-7 transcriptional response during murine early T cell development.
Not available
S-EPMC5643372 | biostudies-literature
UnknownFAT1 expression in T-cell acute lymphoblastic leukemia (T-ALL) modulates proliferation and WNT signaling.
Not available
S-EPMC9849452 | biostudies-literature
Transcriptomicsgene expression profiling in CD69 positive blood cells selected from Healthy blood Donors and HTLV-1-infected patients
The goal of the study was to identify difference in gene expression between activated /CD69+ blood cells selected from HTLV-1-infected patient displaying HAM-TSP disease (HTLV-1-associated myelopathy/tropical spastic paraparesis), compared to healthy blood donor /HD (biological sample providers: Dr....
ORGANISM(S): Homo sapiens 
2012-03-14 | E-GEOD-33859 | biostudies-arrayexpress
UnknownChimeric MHC class I- and II-restricted non-self epitopes broaden antitumor T cell reactions.
Not available
S-EPMC12679993 | biostudies-literature
UnknownInterleukin 2 modulates thymic-derived regulatory T cell epigenetic landscape.
Not available
S-EPMC6299086 | biostudies-literature
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