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ProteomicsLow kindlin-3 levels in osteoclasts of kindlin-3 hypomorphic mice result in osteopetrosis due to leaky sealing zones
Osteoclasts form special integrin-mediated adhesion structures called sealing zones that enable them to adhere to and resorb bone. Sealing zones consist mainly of densely packed podosomes tightly inter-connected by actin fibers. Their formation requires the presence of the hematopoietic integrin reg...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-25 | PXD026711 | Pride
Sealing zone Podosome Osteoclast Bone resorption Kindlin-3 Integrin 
TranscriptomicsTargeting genes of AP-2d in the mouse midbrain
Identification of AP-2d target genes in the midbrain of E15 mouse embryos RNA from a pool of 15 E15 mouse midbrains from control and AP-2d knockout embryos
ORGANISM(S): Mus musculus 
2011-07-31 | E-GEOD-27296 | biostudies-arrayexpress
OtherCopy number analysis of the murine platelet proteome spanning the complete abundance range.
Data from ProteomeXchange, PXD ID: PXD000747. Experiment: EXQ4_MaZe_SA_P4, file: folder summary. Published as part of Mol Cell Proteomics. 2014 Dec;13(12):3435-45 . From the Abstract: {{i}} ... Using recent technological advances, we here characterized the proteome of murine platelets, key actors i...
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM32320017734 | GPMDB
Resource Reanalysis 
ProteomicsM.musculus - Platelet, SC (Zeileretal,molcellproteomics2014)
abundance based on Spectral counting, Interaction consistency score: 15.1, Coverage: 17
ORGANISM(S): 10090 
2014-00-00 | 1935546345 | PAXDB
ProteomicsAnti-FLAG co-immunoprecipitation of N- or C-terminally FLAG-HA-tagged FAM98A, FAM98B and FAM98C, from HEK Flp-In T-REx 293 cells.
Determination of the interactome of different human FLAG-HA-tagged FAM98 paralogs (FAM98A, FAM98B and FAM98C) by co-immunoprecipitation/MS. Two expression constructs were used per paralog: one with an N-terminal and one with a C-terminal FLAG-HA-tag. Expression constructs were stably integrated into...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD076703 | Pride
ProteomicsFAM98C KO validation in HEK Flp-In T-REx 293 cells.
Validation of a FAM98C KO in HEK Flp-In T-REx 293 cells by quantifying the occurrence of FAM98C-specific peptides in whole cell lysates with LC-MSMS. WT HEK Flp-In T-REx 293 cells were used as control.
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD076694 | Pride
UnknownNine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
Not available
S-EPMC3772747 | biostudies-literature
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