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TranscriptomicsTwo transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon [ChIP-chip data]
Because iron toxicity and deficiency are equally life threatening, maintaining intracellular iron levels within a narrow optimal range is critical for nearly all known organisms. However, regulatory mechanisms that establish homeostasis are not well understood in organisms that dwell in environments...
ORGANISM(S): Halobacterium sp. NRC-1 
2011-06-02 | E-GEOD-29705 | biostudies-arrayexpress
TranscriptomicsHalobacterium salinarum NRC-1 VNG1451C transcription factor ChIP-chip with and without carbon sources
Gene regulatory networks play an important role in coordinating biochemical fluxes through diverse metabolic pathways. The modulation of enzyme levels enables efficient utilization of limited resources as organisms dynamically acclimate to nutritional fluctuations in their environment. Here we hav...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-06 | E-GEOD-13498 | biostudies-arrayexpress
TranscriptomicsTwo transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon
This SuperSeries is composed of the following subset Series: GSE29704: Two transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon [gene expression data] GSE29705: Two transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon [ChIP-chip data] R...
ORGANISM(S): Halobacterium sp. NRC-1 
2011-06-02 | E-GEOD-29706 | biostudies-arrayexpress
TranscriptomicsA role for programmed cell death in the microbial loop
The microbial loop is the conventional model by which nutrients and minerals are recycled in aquatic eco-systems. Biochemical pathways in different organisms become metabolically inter-connected such that nutrients are utilized, processed, released and re-utilized by others. The result is that unrel...
ORGANISM(S): Halobacterium sp. NRC-1 
2013-05-08 | E-GEOD-45752 | biostudies-arrayexpress
TranscriptomicsHalobacterium NRC-1 ura3 parent strain and VNG1451C deletion mutant in response to growth in rich medium
Gene regulatory networks play an important role in coordinating biochemical fluxes through diverse metabolic pathways. The modulation of enzyme levels enables efficient utilization of limited resources as organisms dynamically acclimate to nutritional fluctuations in their environment. Here we hav...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-06 | E-GEOD-13531 | biostudies-arrayexpress
ProteomicsComparison of wildtype and gr1 knock-out mutants of Physcomitrella patens using quantitative proteomics
(1) While it is known that redox-regulation in chloroplasts is vital for functional photosynthesis, the interplay of different redox-cascades in balancing reactive oxygen species (ROS) with metabolic regulation via thiol switching is still partly unresolved. We investigate the importance of the glut...
ORGANISM(S): Physcomitrella patens subsp. patens (Moss) 
2020-05-06 | PXD012843 | Pride
Glutathion reductase Light response Physcomitrella patens Gr1 
UnknownRTS,S/AS01 malaria vaccine mismatch observed among Plasmodium falciparum isolates from southern and central Africa and globally.
Not available
S-EPMC5920075 | biostudies-literature
TranscriptomicsH. salinarum transcriptome dynamics in response to 0.85mM extracellular copper
Halobacterium salinarum is a halophillic archea that is capable of sustaining growth despite dramatic changes to the concentration of ions in its extracellular environment. Here we studied H. salinarum's specific adaptation response to the transition metal copper. Analysis utilized pre-treatment (t...
ORGANISM(S): Halobacterium sp. NRC-1 
2012-06-29 | E-GEOD-39028 | biostudies-arrayexpress
ProteomicsSpectrin-beta 2 facilitates the selective accumulation of GABAA receptors at somatodendritic synapses
Fast synaptic inhibition is dependent on targeting specific GABAAR subtypes to dendritic and axon initial segment (AIS) synapses. Synaptic GABAARs are typically assembled from 1-3, and subunits. Here, we isolate distinct GABAARs from the brain and interrogate their composition using quantitative pr...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD038703 | Pride
Ais Gaba a receptors Spectrins 
ProteomicsA deeply conserved protease, acylamino acid-releasing enzyme (AARE), acts in aging in Physcomitrella and Arabidopsis
Protein oxidation results from the reaction of amino-acid side chains with reactive oxygen species (ROS) and is mostly irreversible. In non-photosynthetic tissues, mitochondria are a main source of ROS, whereas plastids are the major source in photosynthetic tissues. Oxidized proteins suffer from de...
ORGANISM(S): Physcomitrella patens subsp. patens (Moss) 
2023-03-11 | PXD033854 | Pride
Arabidopsis Ageing Physcomitrella Ros Physcomitrium Protein oxidation 
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