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MetabolomicsTaurine ameliorates oxidative stress of BMSCs and promotes osteogenesis in irradiated jaws
Osteoradionecrosis of the jaw (ORNJ) is a complication after head and neck radiotherapy that severely affects patients’ quality of life. Currently, an overall understanding of microenvironmental factors of ORNJ is still lacking. Here, we reveal the activation of taurine metabolism in irradiated mand...
2024-07-08 | MTBLS10284 | MetaboLights
TranscriptomicsEffect of W805EC nanoemulsion (NE) on global gene transcription in JawsII dendritic cells in vitro
Nanoemulsion adjuvant affects immune gene expression in dendritic cells. Microarray was used to asses global changes in gene expression in JAWS II dendritic cells upon treatment with nanoemulsion (NE) adjuvant W805EC JawsII cell were incubated with NE formulation for 6 and 24 hours, and RNA was ext...
ORGANISM(S): Mus musculus 
2013-11-09 | E-GEOD-51804 | biostudies-arrayexpress
UnknownA toll-like receptor-4-interacting surfactant protein-A-derived peptide suppresses tumor necrosis factor-α release from mouse JAWS II dendritic cells.
Not available
S-EPMC3061537 | biostudies-literature
TranscriptomicsRegion-specific gene expression profiling of early mouse mandible uncovered SATB2 as a key molecule for teeth patterning
Mammalian dentition exhibits distinct heterodonty, with more simple teeth located in the anterior area of the jaw and more complex teeth situated posteriorly. While some region-specific differences in signaling have been described previously, here we performed gene expression profiling of anterior a...
ORGANISM(S): Mus musculus 
2024-10-31 | E-MTAB-13604 | biostudies-arrayexpress
ProteomicsPart 2 JAWS; 2'-O-methylation of the second transcribed nucleotide in eukaryotic RNA 5’ cap impacts protein production levels and susceptibility to DXO-mediated transcript degradation
Eukaryotic mRNA 5’ end is decorated with cap structure which plays multiple roles in the cell. Most importantly, protects transcript from exonucleolytic degradation and enables translation of encoded protein conducted by cap-dependent machinery. This is also a key feature in the process of recognizi...
ORGANISM(S): Mus musculus (Mouse) 
2022-09-08 | PXD028635 | Pride
Cap Jaws Mrna 
UnknownEndodontic Infection-induced Inflammation Resembling Osteomyelitis of the Jaws in Toll-like Receptor 2/Interleukin 10 Double-knockout Mice.
Not available
S-EPMC6364571 | biostudies-literature
UnknownA distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle.
Not available
S-EPMC6752947 | biostudies-literature
TranscriptomicsExpression data from E11.5 mouse branchial arch 1 (BA1) - comparison between Ezh2lox/lox and Wnt1Cre Ezh2lox/lox embryos
Conditional ablation of Ezh2 in the neural crest lineage results in loss of the neural crest-derived mesenchymal derivatives. In this data sheet we determine gene expression analysis in Ezh2lox/lox and Wnt1Cre Ezh2lox/lox in E11.5 mouse BA1 cells. Conditional ablation of Ezh2 in the neural crest lin...
ORGANISM(S): Mus musculus 
2013-11-09 | E-GEOD-52220 | biostudies-arrayexpress
TranscriptomicsGenome-wide mapping of expression in WT and p63 mutant mouse mandibular prominences at E10-E13
Despite even large phenotypic differences among vertebrate groups, dentitions and jaws fit and function together, yet the genetic processes that orchestrate cranial and dental morphogenesis remain poorly understood. In the p63-/- mouse mutant, teeth but not jaws fail to form. This edentate mouse is ...
ORGANISM(S): Mus musculus 
2016-12-23 | GSE92769 | GEO
TranscriptomicsGene expression profiling of the mandibular arch from Alk5 mutant mouse models
The overall goal of this project is to investigate the role of TGF-beta signaling in tissue-tissue interactions between myogenic precursors of craniofacial muscles and cranial neural crest cells (CNCCs). Here, we conducted gene expression profiling of the mandibular arch from mice at embryonic day E...
ORGANISM(S): Mus musculus 
2014-06-18 | E-GEOD-52357 | biostudies-arrayexpress
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