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ProteomicsLabel-free quantitative data dependent (DDA) nano-LC-MS/MS analysis of proteomic changes in the mesenteric lymph harvested from healthy (control) and DSS-fed mice models of colitis
The gastrointestinal mucosa constitutes a critical barrier where millions of microbes and environmental antigens can interact with the host immune system. Intestinal barrier defects have been linked to a broad range of pathological states, including autoimmune, cancer and neurodegenerative diseases....
ORGANISM(S): Mus musculus (Mouse) 
2024-08-09 | PXD044885 | Pride
Mouse mesenteric lymph  dda nano-lc/ms/ms 
TranscriptomicsGene expression in PLN vs. ILN or MLN in mice
Normal gene expression in pancreatic lymph nodes compared to inguinal or mesenteric lymph nodes across different strains of mice (BALB/c, FVB, NOD, NOD.B10). Lymph nodes were excised from 12 wk old female mice (5 mice per group), and total RNA was extracted for dual dye microarray analysis.
ORGANISM(S): Mus musculus 
2009-04-23 | E-GEOD-15748 | biostudies-arrayexpress
Proteomicsnano-LC/MS/MS analysis of Human Mesenteric lymph endogenous peptidome isolated from Inflammatory Bowel Disease (IBD) subjects.
A compromised pathology of the intestinal barrier have been associated with a series of inflammatory conditions where the routine controls nutrient absorption and pathogens exclusion is lost to different degrees. When the epithelial barrier is compromised, bacteria and their products can attack the ...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD051024 | Pride
Lyph Peptidome Inflammatory bowel disease 
TranscriptomicsTranscription profiling of mouse Peyers patch and mesenteric lymph nodes after oral infection with Y. enterolitica
To gain a comprehensive view of the host response to pathogens within these tissues, we determined the transcriptional profiles of intestinal lymphatic tissue infected with Y. enterocolitica. Expression analysis using Affymetrix GeneChips revealed a complex host response in the Peyer’s patches (PP) ...
ORGANISM(S): Mus musculus 
2007-11-24 | E-GEOD-4764 | biostudies-arrayexpress
TranscriptomicsExpression data from adult mouse mesenteric arteries
Vascular smooth muscle cells require beta1 integrin for survival. Following the induced deletion of smooth muscle beta1 integrin, smooth muscle cells undergo apoptosis and arteries become fibrotic. This microarray study on mesenteric arteries 2 weeks after the initiation of beta1 integrin deletion s...
ORGANISM(S): Mus musculus 
2013-02-26 | E-GEOD-44663 | biostudies-arrayexpress
MetabolomicsGNPS - Mouse Mesenteric Lymph Node Metabolites
Small molecules extracted from mouse mesenteric lymph nodes.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000080181 | GNPS
ProteomicsLabel free-DDA nano-LC/MS/MS analysis of Human Mesenteric lymph collected from Inflammatory Bowel Disease (IBD) subjects.
Compromise of the intestinal barrier have been associated with a series of inflammatory conditions where the routine controls nutrient absorption and pathogens exclusion is lost to different degrees. The intestinal epithelial cells form a barrier of selective permeability which protects from invasio...
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD044801 | Pride
Lable free-dda Lymphatics Inflammatory bowel disease Lymph 
TranscriptomicsLymphoid tissue specific homing of bone marrow-derived dendritic cells
Because of their potent immunoregulatory capacity, dendritic cells (DCs) have been exploited as therapeutic tools to boost immune responses against tumors or pathogens, or dampen autoimmune or allergic responses. Murine bone marrow-derived DCs (BM-DCs) are the closest known equivalent of the blood m...
ORGANISM(S): Mus musculus 
2009-04-23 | E-GEOD-15784 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse BALBc strain mesenteric lymph nodes after response to common allergens.
In this study, MLN transcriptome profiling of female BALB/c mice was conducted in order to explore the molecular mechanism(s) of antigen sensitization using three of the most common food allergens; BLG, OVA and PNA. Analysis of cDNA microarray data revealed a complex network of genes that is modulat...
ORGANISM(S): Mus musculus 
2011-05-11 | E-MEXP-2676 | biostudies-arrayexpress
TranscriptomicsSpatial transcriptomics from murine inguinal and mesenteric lymph nodes
B cell-interacting reticular cells (BRC) form transcriptionally and topologically stable immune-interacting microenvironments that direct efficient humoral immunity. While several immune niche factors have been elucidated, the cues sustaining BRC function and topology across activation states remain...
ORGANISM(S): Mus musculus 
2023-03-29 | E-MTAB-12468 | biostudies-arrayexpress
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