There is positive causality between coffee consumption and osteoarthritis (OA), however, whether gut microbiota is involved in it needs to be discussed. Here, we observed that, in caffeine consumers, fecal Prevotella copri (P. copri) abundance was positively correlated with subchondral bone mass,...

Background: Osteoarthritis (OA) is a debilitating joint disorder with no effective disease-modifying drugs. Liubao tea, a traditional Chinese dark tea, possesses various bioactivities, including anti-inflammatory and gut microbiota-regulating effects. However, its potential therapeutic role and m...