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TranscriptomicsExpression data from mouse collecting duct cell, mpkCCD, in response to a peptide hormone vasopressin analog, dDAVP
Vasopressin is the major hormone that regulates renal water excretion. It does so by binding to a receptor in renal collecting duct cells, triggering signaling pathways that ultimately regulate the abundance, location, and activity of the water channel protein aquaporin 2. We took an advantage of ...
ORGANISM(S): Mus musculus 
2010-12-09 | E-GEOD-19938 | biostudies-arrayexpress
ProteomicsProteomic and phosphoproteomic analyses of protein PKA catalytic-alpha-null mpkCCD cells and PKA catalytic-beta-null mpkCCD cells.
Protein Kinase A (PKA) is a widely studied protein that has been viewed by most investigators as a single entity, although its catalytic subunits are coded in the genome by two separate genes, PKA catalytic alpha (Gene symbol: Prkaca) and PKA catalytic beta Gene symbol: Prkacb). At an amino-acid le...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-01 | PXD015050 | Pride
Phosphoproteomics Pka catalytic subunit Kidney Pka Mouse Proteomics Kinase Mpkccd 
GenomicsTime-course transcriptome profiling in vasopressin-treated mouse kidney collecting duct mpkCCD
Time-course transcriptome profiling in vasopressin-treated mouse kidney collecting duct mpkCCD
PRJNA686780 | ENA
GenomicsHypertonicity induced changes in gene expression in mpkCCD cells and the contribution of NFAT5 activity on these changes.
Hypertonicity induced changes in gene expression in mpkCCD cells and the contribution of NFAT5 activity on these changes.
PRJNA1446791 | ENA
GenomicsTranscriptome changes in response to dDAVP stimulation in CRISPR/Cas9 mediated Camk2d knock-out mpkCCD cells
Transcriptome changes in response to dDAVP stimulation in CRISPR/Cas9 mediated Camk2d knock-out mpkCCD cells
PRJNA951435 | ENA
GenomicsATAC-Seq analysis in vasopressin-responsive mouse renal collecting duct mpkCCD cells
ATAC-Seq analysis in vasopressin-responsive mouse renal collecting duct mpkCCD cells
PRJNA428530 | ENA
ProteomicsQuantitative proteomic analysis of SUMOylation in renal cortical collecting duct cells after aldosterone stimulation
SILAC was employed to investigate the effect of aldosterone stimulation on SUMOylation of cortical collecting duct (mpkCCD) cells.
ORGANISM(S): Mus musculus (Mouse) 
2019-10-07 | PXD013363 | Pride
Collecting duct Quantitative Renal Silac Kidney Sumoylation 
TranscriptomicsTime-course transcriptome profiling in vasopressin-treated mouse kidney collecting duct mpkCCD
Purpose: The goal of this study is to identify vasopressin-regulated genes in mouse kidney collecting duct cell line mpkCCD. To explore dynamic regulation of vasoressin-mediated transcriptional regulation, transcriptome of vasopressin-treated cells at four different time points (3h, 6h, 12h, and 24h...
ORGANISM(S): Mus musculus 
2021-07-22 | GSE163566 | GEO
TranscriptomicsHypertonicity induced changes in gene expression in mpkCCD cells and the contribution of NFAT5 activity on these changes.
The corticomedullary osmotic gradient between renal cortex and medulla induces a specific spatial gene expression pattern. The factors that control these differences are not fully addressed. The hypertonic environment leads to activation of the nuclear factor of activated T-cells 5 (NFAT5), which re...
ORGANISM(S): Mus musculus 
2026-06-25 | GSE326713 | GEO
TranscriptomicsTranscription profiling of mpkCCDc14 cells cloned into colonies with varying aquaporin 2 (AQP2) expression levels in the presence of vasopressin analogy dDAVP to identify transcripts responsible for cell-specific expression of AQP2
This series of microarray data contain transcript intensity of mpkCCD cells. Experiment Overall Design: The mpkCCDc14 cells were cloned into colonies with varying aquaporin 2 (AQP2) expression levels in the presence of vasopressin analogy dDAVP. Transcript profiling was done for the original cells ...
ORGANISM(S): Mus musculus 
2009-01-31 | E-GEOD-13667 | biostudies-arrayexpress
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