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Protein S-persulfidation (P-SSH) is recognized as a common post-translational modification across all domains of life. It occurs under basal conditions and is often observed to be elevated under stress conditions. However, the mechanism(s) by which proteins are persulfidated inside cells have remain...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD038309 | Pride
MPST sulfurtransferase maintains mitochondrial protein import and cellular bioenergetics to attenuate obesity
To gain insight into the biological processes altered by Mpst deletion, RNA-sequencing was performed using inguinal fat from WT and Mpst-/- mice maintained on high fat diet (HFD).
ORGANISM(S): Mus musculus 
2022-04-26 | GSE201361 | GEO
Recents studies in mice and humans demonstrated the relevance of H2S-synthesising enzymes (such as CTH, CBS and MPST) in adipose tissue physiology and preadipocyte differentiation into adipocytes. Here, we aimed to investigate the combined role of CTH, CBS and MPST in the preservation of adipocyte p...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD032370 | Pride
Protective Role of 3-Mercaptopyruvate Sulfurtransferase (MPST) in the Development of Metabolic Syndrome and Vascular Inflammation
Metabolic syndrome (MetS), a cluster of metabolic abnormalities that occur concurrently that significantly increases the risk of cardiovascular disease and mortality. 3-mercaptopyruvate sulfurtransferase (MPST), a cysteine-catabolizing enzyme that yields pyruvate and hydrogen sulfide (H2S), plays a ...
ORGANISM(S): Mus musculus 
2024-12-23 | GSE273901 | GEO
Mpst Tg mouse transcriptome
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