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ProteomicsMonkeypox and vaccinia virus infection of primary human astrocytes
Primary human astrocytes were infected with either monkeypox virus (MPXV clade IIb lineage), vaccinia virus (VACV: Acambis 2000), or controls (MC=monkeypox control, AC = Vaccinia control) at an MOI of 10 for 6 h. Samples (n=4) were analyzed by LC-MS/MS with label-free quantification where the data w...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-06-21 | MSV000092229 | MassIVE
GenomicsItalian MPXV whole-genome sequencing
MPXV whole-genome sequencing of Italian cases - both clade IIb and Ib.
PRJEB121228 | ENA
GenomicsMPXV Clade I sequence
Submission of fastq files for a Norwegian Clade I MPXV sample
PRJEB114676 | ENA
TranscriptomicsTranscriptomic Insights into the Host Response to MPXV Infection in Human Neuronal Cells
The Monkeypox virus (MPXV) is a neurotropic zoonotic pathogen, as evidenced by neurological symptoms in patients and its demonstrated neuroinvasive potential in both in vitro and in vivo models. However, the host responses and mechanisms underlying MPXV-induced neural damage remain poorly understood...
ORGANISM(S): Homo sapiens 
2025-09-18 | GSE307689 | GEO
OtherAd-MPXV-4_scRNA-TCR_Mouse
Study Goals and Relevance The goal of this study is to systematically compare the immunogenicity, protective efficacy, and inflammatory profiles of intranasal (IN) versus intramuscular (IM) immunization with an adenoviral-vectored mpox vaccine candidate, Ad-MPXV-4, which encodes the MPXV antigens A2...
ORGANISM(S): Mus musculus 
2026-09-22 | GSE347756 | GEO
ProteomicsMultilevel proteomics reveals common and specific host perturbations by Monkeypox and Vaccinia viruses (full proteome)
The global spread of Monkeypox virus (MPXV) has resulted in the urgent need for an in-depth molecular characterization of the virus infection. Multiple omics studies on Vaccinia virus have extended our knowledge of poxvirus pathophysiology (REFs). Nevertheless, there are no comparative studies that ...
ORGANISM(S): Homo sapiens (Human) Monkeypox virus Orthopoxvirus 
2024-07-25 | PXD040811 | Pride
Human Poxvirus Shotgun-proteomics Vaccinia virus Monkeypox virus 
GenomicsTranscriptomic Insights into the Host Response to MPXV Infection in Human Neuronal Cells
Transcriptomic Insights into the Host Response to MPXV Infection in Human Neuronal Cells
PRJNA1322525 | ENA
GenomicsMPXV Systematic Variant Calling (Taskforce VEO)
Systematically called variant data of public MPXV reads
PRJEB55825 | ENA
GenomicsMPXV consensus sequence data produce by the VEO taskforce from public INSDC data
Consensus sequences produced by VEO MPXV Taskforce
PRJEB55824 | ENA
UnknownComparative Analysis of 2022 Outbreak MPXV and Previous Clade II MPXV.
Not available
S-EPMC11600476 | biostudies-literature
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