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ProteomicsIdentification of proximal proteome of MRAS using BioID in U2OS cells
Identification of proximal proteome of MRAS WT and MRAS G22V using BioID in U2OS cells
ORGANISM(S): Homo sapiens (Human) 
2025-01-14 | PXD055944 | Pride
Bioid Mras 
ProteomicsIdentification of proteins co-precipitating with mammalian purified MRAS Q71L
During the purification of recombinantely expressed MRAS and MRAS mutants, there were additional proteins which appeared to co-precipitate and were detected by Coomassie staining. Since the apparent molecular weight was within the range for small GTPase proteins, we sought to determine the identity ...
ORGANISM(S): Homo sapiens (Human) 
2025-01-14 | PXD055948 | Pride
Mras Immunoprecipitation 
Genomics
RNA-seq for MRAS knockdown
PRJNA1168437 | ENA
UnknownMRAS: Master Regulator Analysis of Alternative Splicing.
Not available
S-EPMC12140307 | biostudies-literature
TranscriptomicsKAT7 promotes malignant phenotypes of colorectal cancer via MRAS-mediated activation of the MAPK/ERK pathway
Histone acetyltransferases (HATs) play a crucial role in transcriptional regulation by acetylating histones. Dysregulation of HAT activity is implicated in developmental disorders and cancer. In this study, we discovered an upregulated KAT7 signaling pathway in colorectal cancer (CRC) and its associ...
ORGANISM(S): Homo sapiens 
2024-06-27 | GSE270298 | GEO
UnknownThe small GTPase MRAS is a broken switch.
Not available
S-EPMC11733253 | biostudies-literature
GenomicsKAT7 promotes malignant phenotypes of colorectal cancer via MRAS-mediated activation of the MAPK/ERK pathway
KAT7 promotes malignant phenotypes of colorectal cancer via MRAS-mediated activation of the MAPK/ERK pathway
PRJNA1126153 | ENA
UnknownElucidation of MRAS-mediated Noonan syndrome with cardiac hypertrophy.
Not available
S-EPMC5333962 | biostudies-literature
UnknownStructure of the MRAS-SHOC2-PP1C phosphatase complex.
Not available
S-EPMC9452295 | biostudies-literature
UnknownMRAS: A Close but Understudied Member of the RAS Family.
Not available
S-EPMC6280710 | biostudies-literature
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