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ProteomicsMSI-1 knockdown in MB002 medulloblastoma cell line
MSI-1 is a RNA-binding protein that is required for normal neural stem cell and brain cancer stem cells. To understand its molecular mechanisms in medulloblastoma, we peroformed whole-cell proteomic analysis in MB002 medulloblastoma cells, after knockdown of MSI-1.
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD012432 | Pride
Human Medulloblastoma Msi-1 
GenomicsDickkopf 1 Impairs Sensitivity to PD-1 Blockade through CD8+ T Cell Inactivation in dMMR/MSI Colorectal Cancer
Dickkopf 1 Impairs Sensitivity to PD-1 Blockade through CD8+ T Cell Inactivation in dMMR/MSI Colorectal Cancer
PRJNA627657 | ENA
TranscriptomicsDickkopf 1 Impairs Sensitivity to PD-1 Blockade through CD8+ T Cell Inactivation in dMMR/MSI Colorectal Cancer
Dickkopf 1 (DKK1) could promote tumor progression by suppressing immunity. Therefore, we investigated whether DKK1 influence prognosis and sensitivity to PD-1 blockade in colorectal cancers (CRCs) with defective DNA mismatch repair genes (dMMR) or microsatellite instability (MSI). We found that elev...
ORGANISM(S): Homo sapiens 
2021-04-07 | GSE149206 | GEO
UnknownDrosophila Rbp6 is an orthologue of vertebrate Msi-1 and Msi-2, but does not function redundantly with dMsi to regulate germline stem cell behaviour.
Not available
S-EPMC3507872 | biostudies-literature
TranscriptomicsMRE11 Deficiency Increases Sensitivity to Poly(ADP-ribose) Polymerase Inhibition in Microsatellite Unstable Colorectal Cancers.
We have performed bioinformatic approaches to identify the level of enrichment between gene expression profiles characterizing MSI tumors and gene changes induced in vitro by the PARP-1 inhibitor Phenanthridinone and others using the Connectivity Map tool. In a first step, we have anyzed the express...
ORGANISM(S): Homo sapiens 
2011-04-07 | E-GEOD-26682 | biostudies-arrayexpress
UnknownDual Knockdown of Musashi RNA-Binding Proteins MSI-1 and MSI-2 Attenuates Putative Cancer Stem Cell Characteristics and Therapy Resistance in Ovarian Cancer Cells.
Not available
S-EPMC8584030 | biostudies-literature
UnknownPhosphorylation of MSI-1 is implicated in the regulation of associative memory in Caenorhabditis elegans.
Not available
S-EPMC9555661 | biostudies-literature
UnknownPeptide MSI-1 inhibited MCR-1 and regulated outer membrane vesicles to combat immune evasion of Escherichia coli.
Not available
S-EPMC10443334 | biostudies-literature
UnknownInstability of a dinucleotide repeat in the 3'-untranslated region (UTR) of the microsomal prostaglandin E synthase-1 (mPGES-1) gene in microsatellite instability-high (MSI-H) colorectal carcinoma.
Not available
S-EPMC4523444 | biostudies-literature
UnknownTranscriptomic Profiling of MSI-H/dMMR Gastrointestinal Tumors to Identify Determinants of Responsiveness to Anti-PD-1 Therapy.
Not available
S-EPMC9365358 | biostudies-literature
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