Sort   by:  
 Page size 
TranscriptomicsTranscriptional response to stress in serum deprived mouse fibroblasts in the presence of MSK1/2 inhibitor.
We have employed gene expression profiling in order to identify targets of transcriptional response to stress in resting mouse Swiss 3T3 fibroblasts, either untreated (control) or treated with anisomycin for 3 or 6 hours to induce the p38/MAP kinase pathway. In order determine transcriptional effec...
ORGANISM(S): Mus musculus 
2014-08-12 | E-GEOD-58746 | biostudies-arrayexpress
ProteomicsHOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway via stimulating MSK1 kinase and suppressing PPP2R2B protein
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, which lacks effective therapies. We demonstrated that the transcription factor, HOXC6, was overexpressed in most PDACs, and its inhibition blocked PDAC tumor growth and metastasis. HOXC6 transcriptionally activated the tumor-pr...
ORGANISM(S): Homo sapiens (Human) 
2023-10-31 | PXD041238 | Pride
Pancreatic cancer Hoxc6 Tumor growth Msk1 Metastasis 
ProteomicsHOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway via stimulating MSK1 kinase and suppressing PPP2R2B protein
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, which lacks effective therapies. We demonstrated that the transcription factor, HOXC6, was overexpressed in most PDACs, and its inhibition blocked PDAC tumor growth and metastasis. HOXC6 transcriptionally activated the tumor-pr...
ORGANISM(S): Homo sapiens (Human) 
2023-10-31 | PXD041239 | Pride
Pancreatic cancer Hoxc6 Tumor growth Msk1 Metastasis 
GenomicsCellulophaga omnivescoria strain:MSK1
Cellulophaga omnivescoria strain:MSK1 Genome sequencing
PRJNA917471 | ENA
TranscriptomicsHippocampal Gene Expression Profile of Mitogen Stress activated Kinase 1 (MSK1) null mice.
Analysis of alterations in the hippocampus transcriptome caused by deletion of Mitogen Stress activated Kinase 1 (MSK1). MAPK signaling has been implicated in a wide range of neuronal processes, including development, plasticity and viability. One of the principal downstream targets of both the ERK/...
ORGANISM(S): Mus musculus 
2017-10-31 | GSE98751 | GEO
GenomicsExperience recruits MSK1 to expand the dynamic range of synapses and enhance cognition
Experience recruits MSK1 to expand the dynamic range of synapses and enhance cognition
PRJNA627668 | ENA
UnknownMSK1 activity is controlled by multiple phosphorylation sites.
Not available
S-EPMC1134980 | biostudies-literature
GenomicsMSK1 regulates luminal cell differentiation and metastatic dormancy in breast cancer
For many breast cancer (BCa) patients, symptomatic bone metastases appear after years or even decades of la­tency. How metastatic cells disseminate, and how micromet­astatic lesions remain dormant and undetectable yet initiate colonization, are major questions in cancer research. Here we identify an...
ORGANISM(S): Homo sapiens 
2017-11-13 | GSE100306 | GEO
UnknownMSK1 Downstream Signaling Contributes to Inflammatory Pain in the Superficial Spinal Dorsal Horn.
Not available
S-EPMC12733777 | biostudies-literature
GenomicsHOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway via stimulating MSK1 kinase and suppressing PPP2R2B protein
HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway via stimulating MSK1 kinase and suppressing PPP2R2B protein
PRJNA631537 | ENA
Sort   by:  
 Page size