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The homeoprotein Msx1 and Msx2 involved in normal skeletal muscle development and also contribute to muscle defects if altered during development. Deciphering the downstream signaling networks of Msx1 and Msx2 in myoblasts differentiation will help us to understand the molecular events that contribu...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD026944 | Pride
The impact on reprogramming of Msx2
MSX2 safeguards syncytiotrophoblast fate of human TSCs
RNA-seq Analysis of Msx2fl/fl(Msx2 WT) and Le-Cre+/- Msx2fl/fl(Msx2 CKO) Lens Transcriptomes
The majority of placental pathologies arise from failures in trophoblast differentiation, yet the underlying transcriptional regulation is poorly understood. Here, we use human trophoblast stem cells to elucidate the function of the transcription factor MSX2 in trophoblast specification. We show tha...
ORGANISM(S): Homo sapiens 
2021-08-28 | GSE165970 | GEO
We report that we make the high-profiling for transcriptome to detect the impact on reprogramming of transcription factor Msx2 at different time points during reprogramming. Based on the technology of overexpression and Knock down for Msx2, we can observe the changes of transcriptomes in contrast wi...
ORGANISM(S): Mus musculus 
2018-05-08 | GSE114120 | GEO
In contrast to urodele amphibians and teleost fish, mammals lack the regenerative responses to replace large body parts. Amphibian and fish regeneration uses dedifferentiation, i.e. reversal of differentiated state, as a means to produce progenitor cells to eventually replace damaged tissues. Theref...
ORGANISM(S): Mus musculus 
2015-10-01 | GSE65619 | GEO
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