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The MT1G gene in LUHMES Neurons is a Sensitive Biomarker of Neurotoxicity
Epigenetic regulation of the DNMT1/MT1G/KLF4/CA9 axis synergizes the anticancer effects of sorafenib in hepatocellular carcinoma
Sorafenib, a multiple-kinase inhibitor, has been widely used as a first-line anticancer drug for advanced hepatocellular carcinoma (HCC). However, the development of drug resistance to sorafenib is frequently observed in clinical applications. Potential non-kinase targets of sorafenib have not been ...
ORGANISM(S): Homo sapiens 
2022-04-30 | GSE192771 | GEO
Identification of toxicants that underlie neurological diseases is a neglected area awaiting a valid strategy to identify such toxicants. We sought biomarkers that respond to known neurotoxicants in LUHMES immortalized neurons and evaluated these biomarkers for use in screening libraries of environm...
ORGANISM(S): Homo sapiens 
2020-08-11 | GSE150005 | GEO
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