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TranscriptomicsB cell super-enhancers and regulatory clusters recruit AID tumorigenic activity
The antibody gene mutator AID promiscuously damages oncogenes and B cell identity genes leading to chromosomal translocations and tumorigenesis. Why non-immunoglobulin loci are susceptible to AID activity is unknown. Here we study AID-mediated lesions in the context of nuclear architecture and the B...
ORGANISM(S): Mus musculus 
2014-12-04 | E-GEOD-62063 | biostudies-arrayexpress
UnknownDiscovery of human coronaviruses pan-papain-like protease inhibitors using computational approaches.
Not available
S-EPMC7453225 | biostudies-literature
TranscriptomicsHigh-density deletion bin map of wheat chromosome 7B
Using 270K Nimblegen Comparative Genomic Hybridization (CGH) array on a set of cv. Chinese Spring deletion lines, a total of 3,671 sequence contigs and scaffolds (~7.8% of chromosome 7B physical length) were mapped into nine deletion bins. In our study we have developed 270K CGH Nimblegen array cont...
ORGANISM(S): Triticum aestivum 
2014-05-09 | E-GEOD-57461 | biostudies-arrayexpress
TranscriptomicsComprehensive, high resolution analysis of cis-acting regulatory networks at the alpha globin locus (array)
We have combined the 4C chromosome conformation capture protocol with high throughput, genome-wide sequence analysis to characterise in full a cis-acting regulatory network at a single locus. In contrast to methods which identify large interacting regions (10-1000kb), the 4C approach provides a comp...
ORGANISM(S): Homo sapiens 
2013-06-06 | E-GEOD-42383 | biostudies-arrayexpress
GenomicsEpigenetic modifications induced by Blimp-1 regulate CD8+ T cell memory progression during acute virus infection
Blimp-1 regulates the overall accumulation of virus-specific CD8+ T cells during acute viral infections. Increased proliferation and survival of Blimp-1-deficient CD8+ T cells is promoted by persistent cytokine responsiveness, resulting from sustained expression of CD25 and CD27. Knockdown of thes...
ORGANISM(S): Mus musculus 
2013-10-10 | E-GEOD-48358 | biostudies-arrayexpress
Proteomics4D label free phosphorylation modification omics of 60 human esophageal cancer tissue samples
Phosphoproteome analysis of clinical tissue samples is important in the precision medicine research. Therefore, we used LC-MS/MS to systematically analyze the differential phosphorylation levels of 20 ESCC tumor tissues, paired normal tissue and lymph node metastatic tissue.
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD051858 | Pride
Esophageal cancer Phosphorylation Human Lc-ms/ms 
TranscriptomicsAhringer AR0169_H3K4ME3_N2_L3 B
modENCODE_submission_176 This submission comes from a modENCODE project of Jason Lieb. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: The focus of our analysis will be elements that specify nucleosome positioning and occupancy, control domains of gene expressio...
ORGANISM(S): Caenorhabditis elegans 
2010-07-07 | E-GEOD-22697 | biostudies-arrayexpress
ProteomicsQuantitative Khib proteomic analyses of 20 cases of primary ESCC tumor tissue (T), matched normal tissue (N) and lymph node metastatic tissue (LN)
To obtain the global landscape of Khib in ESCC metastasis, 20 cases of primary ESCC tumor tissue (T), matched normal tissue (N) and lymph node metastatic tissue (LN) were subjected to quantitative Khib proteomic analyses.
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD038252 | Pride
Proteomics Lysine 2-hydroxyisobutyrylation Cancer metastasis 
UnknownPrediction of Autogenous Shrinkage of Concrete Incorporating Super Absorbent Polymer and Waste Materials through Individual and Ensemble Machine Learning Approaches.
Not available
S-EPMC9656842 | biostudies-literature
UnknownComparative analysis of two timepoints on [18F]FAPI-42 PET/CT in various cancers.
Not available
S-EPMC10710973 | biostudies-literature
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