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Meiotic recombination ensures proper chromosome segregation and genetic diversity during gametogenesis, and its disruption leads to infertility. It is known that the dual histone methylation writer–reader system, in which PRDM9 deposits H3K4me3 and H3K36me3 marks at nucleosomes to specify recombinat...
ORGANISM(S): Homo sapiens (Human) 
2026-01-07 | PXD070427 | Pride
The sample was removed from-80℃ and melted on ice. An appropriate amount of TEAB was added to adjust pH 8.0.5 μ L of suspension was used for SDS-PAGE testing.
ORGANISM(S): Homo sapiens (Human) 
2025-06-11 | PXD061479 | Pride
Meiotic recombination ensures proper chromosome segregation and genetic diversity during gametogenesis, and its disruption leads to infertility. It is known that the dual histone methylation writer–reader system, in which PRDM9 deposits H3K4me3 and H3K36me3 marks at nucleosomes to specify recombinat...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2026-01-07 | PXD068838 | Pride
DNA hydroxymethylation (5hmC) represents a new layer of epigenetic regulation in addition to DNA methylation (5mC). The genome-wide patterns of 5hmC distribution in many tissues and cells have recently been revealed by hydroxymethylated DNA immunoprecipitation (hMeDIP) followed by high throughput se...
ORGANISM(S): Mus musculus 
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