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GenomicsDeregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment - ChIPseq
PPARD and RXR genome wide binding in tumor associated macrophages from serous ovarian carcinoma was characterized.
ORGANISM(S): Homo sapiens 
2015-06-01 | E-MTAB-3166 | biostudies-arrayexpress
TranscriptomicsAffymetrix HG-U133A 2.0 Expression data
Expression .CEL files from Affymetrix HG-U133A 2.0 arrays using DNA from 14 human cell lines derived from metastasized melanoma Study of global gene expression differences in malignant melanoma cell lines with or without specific abberations in BRAF NRAS or CDKN2A. UKRV-Mel-16a was wrongly described...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-22787 | biostudies-arrayexpress
ProteomicsInteraction partners of arginyl-tRNA protein transferase in the moss Physcomitrella patens
Protein arginylation is a post-translational modification at the N-terminus of proteins and is crucial for viability and physiology in higher eukaryotes. The lack of arginylation causes severe developmental defects in plants and embryo lethality in Drosophila and in mice. Although several studies in...
ORGANISM(S): Physcomitrella patens subsp. patens (Moss) 
2016-04-19 | PXD003228 | Pride
Moss Protein interaction Co-ip Physcomitrella patens Lc-ms/ms 
TranscriptomicsDeregulation of PPAR-beta/delta target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment - RNAseq
The transcriptome of serous ovarian cancer tumor associated macrophages was characterized. Additionally, their transcription response to PPARD agonists and inverse agonists in cell culture was analyzed.
ORGANISM(S): Homo sapiens 
2015-05-31 | E-MTAB-3167 | biostudies-arrayexpress
TranscriptomicsAffymetrix CytoscanHD Arrays of 113 Osteosarcoma Samples
Osteosarcoma (OS) is the most common primary malignant tumor of bone; it occurs most commonly in the metaphyseal regions of long bones in adolescents and young adults. Conventional osteosarcoma is characterized by complex karyotypes with a high degree of aneuploidy and numerous structural aberration...
ORGANISM(S): Homo sapiens 
2015-11-09 | E-MTAB-3998 | biostudies-arrayexpress
TranscriptomicsSystematic analysis of time resolved transcriptional signature of the cross-talk between HGF and IL-6 refines the role of Cxcl10 in hepatocyte proliferation control
Liver regeneration is characterized by a scheduled sequence of inner and intra-cellular signaling events. It starts with an initial inflammatory phase, followed by a period of rapidly proliferating hepatocytes and stopping abruptly when the liver mass is restored. The cytokines hepatocellular growth...
ORGANISM(S): Mus musculus 
2016-06-01 | E-GEOD-69928 | biostudies-arrayexpress
UnknownSomatostatin triggers local cAMP and Ca2+ signaling in primary cilia to modulate pancreatic β-cell function
Not available
S-SCDT-10_1038-S44318-025-00383-7 | biostudies-other
ModelsSobotta2017 - IL-6-induced JAK1-STAT3-signaling
Here we present a mathematical model of IL-6-induced JAK1-STAT3 signaling that quantitatively links physiological IL-6 concentrations to the dynamics of IL-6-induced signal transduction and expression of target genes in hepatocytes. The mathematical model consists of coupled ordinary differential eq...
2023-07-05 | MODEL2307050001 | BioModels
UnknownMetabolic shift underlies recovery in reversible infantile respiratory chain deficiency
Not available
S-SCDT-EMBOJ-2020-105364-T | biostudies-other
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