Sort   by:  
 Page size 
UnknownH3F3A K27M mutations in thalamic gliomas from young adult patients.
Not available
S-EPMC3870821 | biostudies-literature
TranscriptomicsTranscription profiling of temporal expression patterns in rat hippocampi of hypoxia tolerant and sensitive animals analyzed 0, 1, 3, 12, 24, and 48 hours after ischemia operation
Comparison of time-series gene expression pattern in hippocampus of hypoxia tolerant or sensitive rats. At 12 time-points ({0h, 1h, 3h, 12h, 24h, 48h} x 2) after ischemia operation, microdissected CA1 regions of the two groups were respectively subjected to oligonucleotide-based microarray analysis....
ORGANISM(S): Rattus norvegicus 
2007-10-30 | E-GEOD-1357 | biostudies-arrayexpress
TranscriptomicsThe target genes of EGFR activity in glioma cells
As a first step towards identifying the target genes of EGFR activity in glioma cells, genome-wide expression analyses were performed using the Affymetrix GeneChip Human Genome U133A array. To accomplish this, mRNA expression levels of these genes were measured in the glioblastoma cell lines, U87 an...
ORGANISM(S): Homo sapiens 
2011-11-05 | E-GEOD-33442 | biostudies-arrayexpress
GenomicsSpatial and temporal evolution of distal 10q deletion, a prognostically unfavorable event in diffuse low-grade gliomas
Background: The disease course of patients with diffuse low-grade glioma is notoriously unpredictable. Temporal and spatially distinct samples may provide insight into the evolution of clinically relevant copy number aberrations (CNAs). The purpose of this study is to identify CNAs that are indicati...
EGAS00001000643 | EGA
UnknownThe target genes of EGFR activity in glioma cells
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-33442 | biostudies-other
Genomicsena-DATASET-VUMC-CCA-03-09-2014-18:57:30:134-11 - samples
Background: The disease course of patients with diffuse low-grade glioma is notoriously unpredictable. Temporal and spatially distinct samples may provide insight into the evolution of clinically relevant copy number aberrations (CNAs). The purpose of this study is to identify CNAs that are indicati...
EGAD00001001000 | EGA
GenomicsGene fusion discovery through RNA sequencing of nine human glioblastoma stem cell lines

We used massively parallel, paired-end sequencing of expressed transcripts (RNA-seq) to detect novel gene fusions in short-term cultures of glioma stem-like cells freshly isolated from nine patients carrying primary glioblastoma multiforme (GBM). The culture of primary GBM tumors under serum-free...

phs000505.v1.p1 | EGA
GenomicsEvolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment.
Temozolomide (TMZ) increases the overall survival of patients with glioblastoma (GBM), but its role in the clinical management of diffuse low-grade gliomas (LGG) is still being defined. DNA hypermethylation of the O 6 -methylguanine-DNA methyltransferase (MGMT) promoter is associated with an improve...
EGAS00001001179 | EGA
GenomicsMutational analysis reveals the origin and therapy-driven evolution of recurrent glioma
Tumor recurrence is a leading cause of cancer mortality. Therapies for recurrent disease may fail, at least in part, because the genomic alterations driving the growth of recurrences are distinct from those in the initial tumor. To explore this hypothesis, we sequenced the exomes of 23 initial low-g...
EGAS00001000579 | EGA
GenomicsJ_Costello_20150303_dataset - samples
Dataset contains WES data from 3 astrocytoma patients: blood as control, primary tumor and recurrent tumor
EGAD00001001305 | EGA
Sort   by:  
 Page size