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ProteomicsHuman bone marrow comprise atypical adipocytes with specific lipid metabolism
Under caloric restriction, bone marrow adipocytes (BM-Ad) do not decrease in size conversely to white adipocytes, suggesting their unique metabolic properties. We compared human primary BM-Ad with paired subcutaneous adipocytes (SC-Ad) using proteomic and lipidomic approaches. We found that while SC...
ORGANISM(S): Homo sapiens (Human) 
2020-01-29 | PXD016322 | Pride
Lc-msms Label free quantificatio Human Bone marrow adipocytes 
MetabolomicsIntegrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency
Functional oncogenic links between ErbB2 and ERRα in HER2+ breast cancer patients support a therapeutic benefit of co-targeted therapies. However, ErbB2 and ERRα also play key roles in heart physiology, and this approach could pose a potential liability to cardiovascular health. Herein, using integr...
2022-09-20 | MTBLS795 | MetaboLights
TranscriptomicsTranscriptomic comparison of chlorhexidine tolerant and sensitive Salmonella Typhimurium
Transcriptional profiles of a chlorhexidine tolerant Salmonella Typhimurium were compared to its, chlorhexidine sensitive, isogenic progenitor isolate. RNA was extracted from mid-log phase cells from both isolates, without chlorhexidine exposure and following exposure to 1 µg/ ml of chlorhexidine fo...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2015-06-06 | E-GEOD-59566 | biostudies-arrayexpress
TranscriptomicsABP1-regulated gene expression in etiolated Arabidopsis seedlings
The AUXIN BINDING PROTEIN 1 (ABP1) is an essential plant protein involved in the control of growth and development all along the plant life. This protein was initially identified on its capacity to bind the phytohormone auxin. Binding of auxin to ABP1 was shown to enhance cell expansion of leaf cell...
ORGANISM(S): Arabidopsis thaliana 
2015-04-07 | E-GEOD-46196 | biostudies-arrayexpress
TranscriptomicsProperties and functions of transcriptionally distinct enteric neurons
In our study, we perform single-cell RNA-seq from various genotypes. These different genotypes allow for isolation of all enteric neurons, excitatory enteric neurons, or inhibitory enteric neurons. We also provide single-cell RNA seq for the celiac-mesenteric ganglia, which is home to sympathetic ...
ORGANISM(S): Mus musculus 
2025-10-31 | E-MTAB-15666 | biostudies-arrayexpress
UnknownMicrobiota modulate sympathetic neurons via a gut-brain circuit.
Not available
S-EPMC7367767 | biostudies-literature
UnknownRisk factors for early mortality from lung cancer: evolution over the last 20 years in the French nationwide KBP cohorts.
Not available
S-EPMC11214995 | biostudies-literature
UnknownPertuzumab Plus Trastuzumab With or Without Chemotherapy Followed by Emtansine in ERBB2-Positive Metastatic Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial.
Not available
S-EPMC10416088 | biostudies-literature
UnknownClassification of 101 BRCA1 and BRCA2 variants of uncertain significance by cosegregation study: A powerful approach.
Not available
S-EPMC8546044 | biostudies-literature
UnknownGenomic analyses inform on migration events during the peopling of Eurasia.
Not available
S-EPMC5164938 | biostudies-literature
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