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ProteomicsLectin-based affinity enrichment and characterization of N-glycoproteins from the human tear film by mass spectrometry
Glycosylation of proteins is one of the most common post-translational modification (PTM) and plays important regulatory functions in diverse biological processes such as protein stability or cell signaling. Accordingly, glycoproteins are also a consistent part of the human tear film proteome mainta...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2023-01-25 | PXD038280 | Pride
N-glycoproteins Mass spectrometry Pngase f Tear film Multi-lectin column 
UnknownA proteomics platform combining depletion, multi-lectin affinity chromatography (M-LAC), and isoelectric focusing to study the breast cancer proteome.
Not available
S-EPMC3148019 | biostudies-literature
ProteomicsGlycoproteomics Landscape of Asymptomatic and Symptomatic Human Alzheimer's Disease Brain
Alterations of protein abundance and post-translational modifications in patients with Alzheimer’s disease (AD), such as glycosylation, phosphorylation, and ubiquitination, and their roles in disease progression and treatment outcome are areas of intense study. Little is known, however, about...
ORGANISM(S): Homo sapiens (Human) 
2022-10-31 | PXD032219 | Pride
Glycoproteins Mass spectrometry Glycoproteomics Alzheimer's 
UnknownLectin-Based Affinity Enrichment and Characterization of N-Glycoproteins from Human Tear Film by Mass Spectrometry.
Not available
S-EPMC9864693 | biostudies-literature
UnknownComparative proteomics and glycoproteomics of plasma proteins in Indian visceral leishmaniasis.
Not available
S-EPMC4179796 | biostudies-literature
TranscriptomicsMicroRNA profiling of mouse bone marrow-derived mast cells during mucosal differentiation and IgE-mediated activation
The aim of this study was to investigate microRNA expression pattern and its functional relevance on the commitment toward mucosal differentiation and on IgE-mediated activation of mast cells. To identify microRNA genes the expression of which change during the differentiation and activation of muri...
ORGANISM(S): Mus musculus 
2011-01-01 | E-GEOD-24321 | biostudies-arrayexpress
ProteomicsMulti-Omics Analysis to Characterize Molecular Adaptation of Entamoeba histolytica during Serum Stress
Entamoeba histolytica is a human pathogen, responsible for amoebic dysentery and invasive extraintestinal disease. The parasite faces several types of stress within the host, and to establish a successful infection it must generate a robust adaptive response against host defense mechanisms. In order...
ORGANISM(S): Entamoeba histolytica 
2022-09-23 | PXD031921 | Pride
Multi-omics E.histolytica Adaptive response 
ProteomicsIdentification and relative quantification of hFSH glycoforms in women sera by PRM MS based approach.
This study presents an alternative preliminary strategy to identify and quantify serum hFSH glycoforms based on immunopurification assay and mass spectrometry (MS) using parallel reaction monitoring (PRM) analysis. In this study, we provide MS-PRM data acquisition method for hFSH glycopeptides ident...
ORGANISM(S): Homo sapiens (Human) 
2021-06-15 | PXD025585 | Pride
Prm-mass spectrometry  fsh  glycosylation 
GenomicsMaternal Nutrition Induces Pervasive Gene Expression Changes but no Detectable DNA Methylation Differences in the Liver of Adult Offspring [RRBS]
Aims: Epidemiological and animal studies have shown that maternal diet can influence metabolism in adult offspring. However, the molecular mechanisms underlying these changes remain poorly understood. Here, we aim to explore phenotypes induced by maternal obesity in a mouse model and examine gene ex...
ORGANISM(S): Mus musculus 
2014-03-04 | E-GEOD-52266 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human miRNA expression in mesenchymal stem cells in young and old donors.
Mesenchymal stem cells were isolated from several donors of different age (young vs old), and total RNA was extracted. Samples were labeled with Cy3 and Cy5 dyes and hybridized in a looped design that allowed the calculation of differentially expressed miRNAs in MSCs isolated from healthy, aged indi...
ORGANISM(S): Homo sapiens 
2010-04-19 | E-MEXP-2455 | biostudies-arrayexpress
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