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MetabolomicsFate and PPARγ and STATs-driven effects of the mitochondrial complex I inhibitor tebufenpyrad in liver cells revealed with multi-omics.
The biological effects of the pesticide and mitochondrial complex I inhibitor tebufenpyrad (TEBU) on liver cells were investigated by combining proteomics and metabolomics. Both cell culture media and cellular lysates were analyzed in dose-response and kinetic experiments on the HepaRG cell line. Re...
2024-02-07 | MTBLS4063 | MetaboLights
TranscriptomicsIntegrative Multi-Omics Reveal Metabolic Reprogramming by Ketogenic Diet in Melanoma Xenografts
The ketogenic diet (KD) has demonstrated anti-proliferative effects across multiple tumor types, yet the underlying metabolic and transcriptomic mechanisms remain incompletely understood. This study employed integrated multi-omics analysis combining targeted metabolomics and RNA-sequencing to elucid...
ORGANISM(S): Homo sapiens 
2026-07-01 | E-MTAB-16979 | biostudies-arrayexpress
ProteomicsBlood and urine multi-omics analysis of the impact of e-vaping, smoking and cessation. From exposome to molecular responses
Cigarette smoking is a major cause of preventable morbidity and mortality. While quitting smoking is the best option, switching from cigarettes to non-combustible alternatives (NCAs) such as e-vapor products is a viable harm reduction approach for smokers who would otherwise continue to smoke. A key...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-01-26 | MSV000091157 | MassIVE
ProteomicsHuman Ebola Virus Disease Pathogenesis Multi-Platform Omics Analysis
Multi-platform omics analyses of peripheral blood mononuclear cells and plasma derived from human patients infected with Ebola virus.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000080129 | MassIVE
TranscriptomicsBlood and urine multi-omics analysis of the impact of e-vaping, smoking and cessation – from exposome to molecular responses
Cigarette smoking is a major cause of preventable morbidity and mortality. While quitting smoking is the best option, switching from cigarettes to non-combustible alternatives (NCAs) such as e-vapor products is a viable harm reduction approach for smokers who would otherwise continue to smoke. A key...
ORGANISM(S): Homo sapiens 
2024-02-22 | E-MTAB-12751 | biostudies-arrayexpress
TranscriptomicsSNP array Multi-omics molecular profiling of primary prostate adenocarcinoma
Multi-omics molecular profiling was performed on post-radical prostatectomy material from a cohort of 132 patients with localized prostate adenocarcinoma. Unsupervised classification techniques were used to build a comprehensive classification of prostate tumours based on three molecular levels: DNA...
ORGANISM(S): Homo sapiens 
2018-07-09 | E-MTAB-6127 | biostudies-arrayexpress
TranscriptomicsSNP array for Multi-omics molecular profiling of primary prostate adenocarcinoma
Multi-omics molecular profiling was performed on post-radical prostatectomy material from a cohort of 132 patients with localized prostate adenocarcinoma. Unsupervised classification techniques were used to build a comprehensive classification of prostate tumours based on three molecular levels: DNA...
ORGANISM(S): Homo sapiens 
2018-06-24 | E-MTAB-6126 | biostudies-arrayexpress
TranscriptomicsMethylation array for Multi-omics molecular profiling of primary prostate adenocarcinoma
Multi-omics molecular profiling was performed on post-radical prostatectomy material from a cohort of 132 patients with localized prostate adenocarcinoma. Unsupervised classification techniques were used to build a comprehensive classification of prostate tumours based on three molecular levels: DNA...
ORGANISM(S): Homo sapiens 
2018-06-24 | E-MTAB-6131 | biostudies-arrayexpress
TranscriptomicsExpression array for Multi-omics molecular profiling of primary prostate adenocarcinoma
Multi-omics molecular profiling was performed on post-radical prostatectomy material from a cohort of 132 patients with localized prostate adenocarcinoma. Unsupervised classification techniques were used to build a comprehensive classification of prostate tumours based on three molecular levels: DNA...
ORGANISM(S): Homo sapiens 
2018-06-24 | E-MTAB-6128 | biostudies-arrayexpress
GenomicsMulti-omics RNA profiling of glioblastoma patient tissues
Multi-omics profiling of paired primary and recurrent glioblastoma patient tissues
EGAD00010001895 | EGA
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