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Extracellular vesicles (EVs) play a pivotal role in various biological pathways, such as immune responses and the progression of diseases, including cancer. However, it is challenging to isolate EVs at high purity from blood plasma and other biofluids due to their low abundance compared to more pred...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD043956 | Pride
We collected 120 ml of xylem exudate from the cut surface of the first internodes from the hypocotyls of the tomato plants at 45 DAG for five hours. The exudates were purified using the gel-free method that we developed previously (Okamoto et al., 2015, Plant J.). Using gel filtration chromatography...
ORGANISM(S): Cellular Organisms 

Acute myeloid leukemia (AML) is an aggressive disease with a high relapse rate. In this study, we map the metabolic profile of CD34+(CD38low/-) AML cells and the extracellular vesicle signatures in circulation from AML patients at diagnosis. CD34+ AML cells display high antioxidant glutathione le...

2024-12-04 | MTBLS11746 | MetaboLights
Carica papaya leaf decoction, an Australian Aboriginal remedy, has been used widely for its healing capabilities against cancer, with numerous anecdotal reports. In this study we investigated its in vitro cytotoxicity on human squamous cell carcinoma cells followed by metabolomic profiling of Carica...
2017-05-04 | MTBLS274 | MetaboLights
Background: COVID-19 has been a global pandemic affecting millions since March 2020. Both as a disease and as a syndrome, COVID19 mimics a number of other clinical entities. Also, current set of investigations such as RT-PCR and antibody based assays are not that efficient in diagnosis of the diseas...
ORGANISM(S): Homo sapiens (Human) 
2026-08-24 | PXD067986 | Pride
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