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ProteomicsIntegrative proteomic and transcriptomic profiling identifies unique and shared functions of oncogenic KRAS and RIT1
Lo A, Holmes K, Mundt F, Moorthi S, Fung I, Fereshetian S, Watson J, Carr SA, Mertins P, Berger A. Aberrant activation of RAS oncogenes is a prevalent event in lung adenocarcinoma, with somatic mutation of KRAS occurring in ~30% of tumors. Recently, we identified somatic mutation of the RAS-family G...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-04-03 | MSV000085225 | MassIVE
ProteomicsProteomics, post-translational modifications, and integrative analyses reveal heterogeneity of molecular mechanisms within medulloblastoma subgroups
Archer TC, Ehrenberger T, Mundt F, Gold MP, Krug K, Mah CK, Mahoney EL, Daniel CJ, LeNail A, Ramamoorthy D, Mertins P, Mani DR, Zhang H, Gillette MA, Clauser K, Noble M, Tang LC, Francois JP, Silterra J, Jensen J, Tamayo P, Korshunov A, Pfister SM, Kool M, Northcott PA, Sears RC, Lipton JO, Carr SA,...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-07-20 | MSV000082644 | MassIVE
ProteomicsMass spectrometry-based proteomics reveals potential roles of NEK9 and MAP2K4 in resistance to PI3K inhibitors in triple negative breast cancer

Filip Mundt, Sandeep Rajput, Shunqiang Li, Kelly Ruggles, Arshag D. Mooradian, Philipp Mertins, Michael A. Gillette, Karsten Krug, et al., Cancer Res. 2018 May 15;78(10):2732-2746. doi: 10.1158/0008-5472.CAN-17-1990.

Activation of phosphoinositide 3-kinase (PI3K) signaling is frequently obs...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-10-19 | MSV000083050 | MassIVE
ProteomicsHuman pleural effusion LC-MSMS
We screened pleural effusion proteomes of mesothelioma and lung adenocarcinoma patients to identify novel soluble mesothelioma biomarkers. We performed quantitative mass spectrometry-(MS-) based proteomics using isobaric tags for relative and absolute quantification (iTRAQ) and used narrow range imm...
ORGANISM(S): Homo sapiens (Human) 
2014-01-14 | PXD000531 | Pride
Human Ief Pleural effusions Malignant mesothelioma Hirief Msms Lung cancer Itraq Ipg 
UnknownMedical Device Recalls in Radiation Oncology: Analysis of US Food and Drug Administration Data, 2002-2015.
Not available
S-EPMC5518627 | biostudies-literature
UnknownTRPV4 is the temperature-sensitive ion channel of human sperm.
Not available
S-EPMC6051745 | biostudies-literature
TranscriptomicsExpression data generated by syndecan-1 silencing in malignant mesothelioma STAV-AB cell line
The transcriptomic responses of syndecan-1 silencing in a human mesothelioma cell line was followed with microarray analysis. To project the transcriptome analysis on the full-dimensional picture of cellular regulation, we applied a novel method of network enrichment analysis which elucidated signal...
ORGANISM(S): Homo sapiens 
2012-11-01 | E-GEOD-37843 | biostudies-arrayexpress
UnknownAdverse Events Involving Radiation Oncology Medical Devices: Comprehensive Analysis of US Food and Drug Administration Data, 1991 to 2015.
Not available
S-EPMC5193217 | biostudies-literature
ProteomicsHs_Pleural_Effusion_8plex
Human pleural effusion LC-MSMS, 8plex
ORGANISM(S): Homo Sapiens (human) 
2014-12-31 | PAe005065 | PeptideAtlas
ProteomicsOrgan-specific metabolic pathways distinguish prediabetes, type 2 diabetes and normal tissues
Defects in pancreatic islets and the progression of multi-tissue insulin resistance in combination with environmental factors are the main causes of type 2 diabetes (T2D). Mass spectrometry-based proteomics of five key-metabolic tissues on a cohort of 42 multi-organ donors provided deep coverage of ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-12 | PXD027597 | Pride
Pancreatic islets Proteomics Type 2 diabetes Serum Liver Skeletal muscle Visceral adipose tissue (vat) 
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