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MetabolomicsMuRF1-Related Metabolomic Changes in Stretched and Unloaded HL-1 Cells
Not available
ORGANISM(S): Mus musculus 
ST000925 | MetabolomicsWorkbench
MetabolomicsTargeted metabolomics of MuRF1 overexpressing cardiomyocytes compared to their wildtype controls (part I)
Not available
ORGANISM(S): Mus musculus 
ST000429 | MetabolomicsWorkbench
MetabolomicsMuRF1-Related Metabolic Alterations in HL-1 Cardiomyocyte Induced by Cyclic Stretch
Not available
ORGANISM(S): Mus musculus 
ST000924 | MetabolomicsWorkbench
TranscriptomicsMuRF1 regulation of Fenofibrate’s induction of spontaneous cardiac hypertrophy in vivo.
MuRF1 -/- w/ Fenofibrate treatment leads to the reduction of proteolytic and fibrolytic enzymes, increasing hypertrophy Four strain-matched groups of 3-8 week old mice were investigated: 1) MuRF1 -/- Fenofibrate feed; 2) MuRF1 -/- chow feed; 3) MuRF1 +/+ Fenofibrate feed; 4) MuRF1 +/+ chow feed at...
ORGANISM(S): Mus musculus 
2016-03-01 | E-GEOD-68480 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse heart from MuRF1 MrRF2 doble knockout vs. wildtype to analyze signalling athways involving MurF1 and MuRF2
Two genes coding for potential muscle signaling proteins were knocked out (MuRF1+2: DKO). RNA of hearts of Wildtype and DKO mice are compared to analyze the signaling pathwayws MuRF1 and MuRF2 are involved in.
ORGANISM(S): Mus musculus 
2008-03-01 | E-MEXP-1027 | biostudies-arrayexpress
MetabolomicsTargeted metabolomics of MuRF1 Knockdown cardiomyocytes compared to their wildtype controls (part II)
Not available
ORGANISM(S): Mus musculus 
ST000430 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of heart from wild type and Murf1/2 double knock out mice
Comparison of the transcriptome of Wildtype versus Murf1/2 double Knock Out (dKO) mouse hearts is analyzed
ORGANISM(S): Mus musculus 
2008-01-15 | E-MEXP-1321 | biostudies-arrayexpress
ProteomicsIdentification of the MuRF1 skeletal muscle ubiquitylome through quantitative proteomics
MuRF1 is a muscle-specific E3 ubiquitin ligase and component of the ubiquitin proteasome system. MuRF1 is transcriptionally upregulated under conditions that cause muscle loss, in both rodents and humans, and is a recognized marker of muscle atrophy. In this study, we used in vivo electroporation ...
ORGANISM(S): Mus musculus (Mouse) 
2021-07-07 | PXD023872 | Pride
Ubiquitin proteomics Muscle atrophy Murf1 Protein degradation Electroporation 
TranscriptomicsCardiac muscle ring finger-1 increases susceptibility to heart failure by inhibiting creatine kinase activity in vivo
Muscle ring finger-1 (MuRF1) is a muscle-specific protein implicated in the regulation of cardiac myocyte size and contractility. MuRF2, a closely related family member, redundantly interacts with protein substrates, and hetero-dimerizes with MuRF1. Mice lacking either MuRF1 or MuRF2 are phenotypica...
ORGANISM(S): Mus musculus 
2009-06-03 | E-GEOD-11661 | biostudies-arrayexpress
ProteomicsBlocking muscle wasting via deletion of the muscle specific E3 ligase MuRF1 impedes pancreatic tumor growth - proteome dataset
Cancer-induced muscle wasting reduces quality of life, complicates or precludes cancer treatments, and predicts early mortality. Herein, we investigated the requirement of the muscle-specific E3 ubiquitin ligase, MuRF1, for muscle wasting induced by pancreatic cancer. Murine pancreatic cancer (KPC) ...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-15 | PXD039158 | Pride
Cancer cachexia Murf1 Muscle wasting Pancreatic cancer 
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