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ProteomicsKaposi’s sarcoma-associated herpesvirus induces specialised ribosomes to efficiently translate viral lytic mRNAs
Historically, ribosomes have been viewed as unchanged homogeneous macromolecular machines with no intrinsic regulatory capacity for mRNA translation. However, an emerging concept is that heterogeneity of ribosomal composition exists, which can exert a regulatory function or specificity in translatio...
ORGANISM(S): Homo sapiens (Human) Human herpesvirus 8 strain rKSHV.219 
2022-12-21 | PXD032318 | Pride
Microbiology/virology/herpes virus/human/specalised ribosome/ribosome biogenesis 
ProteomicsThe Kaposi’s sarcoma-associated herpesvirus ORF11 protein interacts with pre-ribosome complexes during lytic replication
Historically, ribosomes have been viewed as unchanged homogeneous macromolecular machines with no intrinsic regulatory capacity for mRNA translation. However, an emerging concept is that heterogeneity of ribosomal composition exists, which can exert a regulatory function or specificity in translatio...
ORGANISM(S): Homo sapiens (Human) Human herpesvirus 8 strain rKSHV.219 
2022-12-21 | PXD032367 | Pride
Microbiology/kaposi’s sarcoma-associated herpesvirus/specalised ribosomes/ribosome biogenesis 
TranscriptomicsDynamics of gene expression changes in epithelial and mesenchymal HMLER cell lines transitioning from suspension 3D culture to adhesion cultures
In order to metastasize, few cells need to detach from the primary tumor, and transition through the circulation to distant sites to establish new solid tumor metastases. The gene expression changes occurring between these transitions are poorly understood, and controversial findings have been repor...
ORGANISM(S): Homo sapiens 
2015-07-10 | E-GEOD-70279 | biostudies-arrayexpress
GenomicsData Access Commitee for gastric cancer ascites
Data Access Committee EGAC00001001026
EGAC00001001026 | EGA
Genomicsc9d38693-41de-4186-90c3-5e52d1913254 - samples
Whole-exome sequencing (WES) was performed on a total of 34 PC specimens, with 15 cases having matched gDNAs extracted from blood.
EGAD00001004364 | EGA
Genomics32c6825c-80c0-4d0f-9284-cc7c1a39e68a - samples
Whole transcriptome sequencing (RNA-seq) was performed on 39 PC specimens. Among them, 21 specimens also had WES data.
EGAD00001004365 | EGA
GenomicsProfiling of Peritoneal Metastases from Gastric Adenocarcinoma Identified Molecular Subtypes
Peritoneal carcinomatosis (PC) occurs frequently in gastric adenocarcinoma (GAC) patients and confers poor prognosis. Multiplex profiling of primary GACs has been insightful but the underpinnings of PC’s development/progression remain largely unknown. Here we characterized exome/transcriptome/immune...
EGAS00001003180 | EGA
UnknownA 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity.
Not available
S-EPMC4841173 | biostudies-literature
UnknownDesign and conduct of the CALERIE study: comprehensive assessment of the long-term effects of reducing intake of energy.
Not available
S-EPMC3032519 | biostudies-literature
UnknownAntiplatelet therapy and the effects of B vitamins in patients with previous stroke or transient ischaemic attack: a post-hoc subanalysis of VITATOPS, a randomised, placebo-controlled trial.
Not available
S-EPMC3361667 | biostudies-literature
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