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Human Cytomegalovirus (HCMV) is a ubiquitous pathogen that has co-evolved with its host and in doing so, is highly efficient in undermining antiviral responses that limit successful infections. As a result, HCMV infections are highly problematic in individuals with weakened or underdeveloped immune ...
ORGANISM(S): Homo sapiens (Human) 
2020-07-03 | PXD019208 | Pride
The Murphy Roth Large (MRL) mouse, a strain capable of regenerating right ventricular myocardium, has a high post-myocardial infarction (MI) survival rate compared with C57BL6/J (C57) mice. The biological processes responsible for this survival advantage are unknown. We compared acute post-MI gene e...
ORGANISM(S): Mus musculus 
We sought to better understand the mechanism of acid-induced cell death in Saccharomyces boulardii--a probiotic yeast routinely used to prevent and treat gastrointestinal disorders. To do this we generated microarray gene expression profiles of S. boulardii cells cultured in an acidic environment. T...
ORGANISM(S): Saccharomyces boulardii 
Staphylococcus aureus is an opportunistic pathogen that colonizes the anterior nares of 30-50% of the population. Colonization is most often asymptomatic, however, self-inoculation can give rise to potentially fatal infections of the deeper tissues and blood. Like all bacteria, S. aureus is able to ...
ORGANISM(S): Staphylococcus aureus (strain USA300) 
2021-03-10 | PXD023039 | Pride
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