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TranscriptomicsInduction of interferon-stimulated genes on the IL-4 response axis by Epstein-Barr virus infected human B cells; relevance to cellular transformation.
Epstein-Barr virus (EBV) is an oncogenic virus that is associated with the pathogenesis of several human lymphoid malignancies, including Hodgkin's lymphoma. Infection of normal resting B cells with EBV results in activation to lymphoblasts that are phenotypically similar to those generated by physi...
ORGANISM(S): Homo sapiens 
2014-02-03 | E-GEOD-45829 | biostudies-arrayexpress
TranscriptomicsLMP1 mediated gene expression changes in transfected CD10+ GC B cells
In this study, we have investigated the effect of LMP1 on gene expression in normal human GC B cells using a non-viral vector based system Experiment Overall Design: Gene expression was compared between LMP1-transfected and control vector-transfected GC B cells from three patients. RNA from the FACS...
ORGANISM(S): Homo sapiens 
2008-10-26 | E-GEOD-10821 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HL cell line associated gene expression changes compared with CD10+ GC B cells
Gene expression was compared between four B-cell derived HL cell lines (L428, L1236, L591, KMH2) and GC B cells from three different patients. Experiment Overall Design: Gene expression was compared between four B-cell derived HL cell lines (L428, L1236, L591, KMH2) and GC B cells from three differe...
ORGANISM(S): Homo sapiens 
2008-10-26 | E-GEOD-10831 | biostudies-arrayexpress
TranscriptomicsDown-regulation of BLIMP1-alpha by the EBV oncogene, LMP1, disrupts the plasma cell differentiation program and prevents viral replication in B cells
In this study, we have investigated the effect of BLIMP1α on gene expression, cell differentiation and pathogenesis in normal human GC B cells using a non-viral vector based system Gene expression was compared among BLIMP1α, LMP1-transfected and control vector-transfected GC B cells from two patient...
ORGANISM(S): Homo sapiens 
2011-07-26 | E-GEOD-27670 | biostudies-arrayexpress
TranscriptomicsKDM6B-induced gene expression changes in transfected CD10-positive GC B cells
In this study, we have investigated the effect of lysine-specific demethylase 6B (KDM6B) on gene expression in normal human germinal center (GC) B cells using a non-viral vector-based system. Gene expression was compared between KDM6B-transfected and control vector-transfected GC B cells from three ...
ORGANISM(S): Homo sapiens 
2011-07-26 | E-GEOD-24044 | biostudies-arrayexpress
TranscriptomicsLMP2A mediated gene expression changes in transfected CD10+ GCB cells
In this study, we have investigated the effect of LMP2A on gene expression in normal human GC B cells using a non-viral vector based system Keywords: transfection of viral oncogene in normal human B cells Gene expression was compared between LMP2A-transfected and control vector-transfected GC B cell...
ORGANISM(S): Homo sapiens 
2013-04-19 | E-GEOD-46143 | biostudies-arrayexpress
UnknownUV-B irradiation promotes anthocyanin biosynthesis in the leaves of <i>Lycium ruthenicum Murray</i>.
Not available
S-EPMC11485054 | biostudies-literature
TranscriptomicsDownregulation of integrin receptor signalling genes by EBV EBNA 3C
Comparsion of cellular gene expression between a control B lymphoma cell-line (BJAB pz2) stably transfected with an empty vector and a BJAB cell-line stably expressing Epstein-Barr virus EBNA 3C (BJAB E3C-4). These cell lines are described in Wang, F., C. Gregory, C. Sample, M. Rowe, D. Liebowitz, R...
ORGANISM(S): Homo sapiens 
2012-03-13 | E-MEXP-3585 | biostudies-arrayexpress
TranscriptomicsTranscriptional profile of B. theta and E. rectale growing in the cecum of mice fed different diets
The adult human gut microbial community is typically dominated by two bacterial phyla (divisions), the Firmicutes and the Bacteroidetes. Little is known about the factors that govern the interactions between their members. Here we examine the niches of representatives of both phyla in vivo. Finishe...
ORGANISM(S): Eubacterium rectale 
2010-05-22 | E-GEOD-14709 | biostudies-arrayexpress
UnknownConservation implications of turtle declines in Australia's Murray River system.
Not available
S-EPMC6374471 | biostudies-literature
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