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TranscriptomicsInnervated and 2 month Denervated Rat EDL muscles
The right legs of 8 Brown-Norway male rats were denervated by a high sciatic nerve section in the hip region of the hind limb.Two months after denervation (6 months of age), extensor digitorum longus (EDL) muscles were removed from the operated legs. The EDL muscles from 8 age-matched non-operated r...
ORGANISM(S): Rattus norvegicus 
2004-09-10 | E-GEOD-1741 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of skeletal muscles treated with a soluble activin type IIB receptor
Inhibition of the myostatin signaling pathway is emerging as a promising therapeutic means to treat muscle wasting disorders. Activin type IIB receptor is the putative myostatin receptor, and a soluble activin receptor (ActRIIB-Fc) has been demonstrated to potently inhibit a subset of TGF-β family m...
ORGANISM(S): Mus musculus 
2011-02-04 | E-GEOD-25306 | biostudies-arrayexpress
GenomicsHDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibroadipogenic progenitors in dystrophic muscles
Fibro-adipogenic progenitors (FAPs) are emerging cellular components of the skeletal muscle regenerative environment. The alternative functional phenotype of FAPs - either supportive of muscle regeneration or promoting fibro-adipogenic degeneration M-bM-^@M-^S is a key determinant in the pathogenesi...
ORGANISM(S): Mus musculus 
2014-04-02 | E-GEOD-52062 | biostudies-arrayexpress
TranscriptomicsmicroRNA profiling of extraocular muscles
The extraocular muscles (EOMs) are a unique group of muscles that are anatomically and physiologically distinct from other skeletal muscles. Previously, we and others have shown that EOMs have a unique transcriptome and proteome. Here, we investigated the expression pattern of microRNAs (miRNAs) in ...
ORGANISM(S): Mus musculus 
2010-05-18 | E-GEOD-18538 | biostudies-arrayexpress
ProteomicsA mitochondrial proteome profile of type 2 diabetes mellitus in skeletal muscles
The goal of the project is to understand the mitochondrial proteome profiles related to T2DM. We performed comprehensive proteome profiling of mitochondria isolated from skeletal muscles in nine T2DM patients and nine control subjects with normal glucose tolerance (NGT).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-03-13 | MSV000083560 | MassIVE
TranscriptomicsTranscription profiling of mouse masseter and tibialis anterior muscles to determine expression differences between muscle groups
Masseter and Tibialis anterior muscles from adult female control mice to determine expression differences between muscle groups
ORGANISM(S): Mus musculus 
2007-10-11 | E-MEXP-1288 | biostudies-arrayexpress
MetabolomicsIsolated murine skeletal muscles utilize pyruvate over glucose for oxidation:Part 2
Not available
ORGANISM(S): Mus musculus 
ST002426 | MetabolomicsWorkbench
TranscriptomicsInfluence of hyperthyroid conditions on gene expression in rat extraocular muscles
Extraocular muscles (EOMs) are a highly specialized type of tissue with a wide range of unique properties, including characteristic innervation, development, and structural proteins. Even though EOMs are frequently and prominently involved in thyroid-associated diseases, little is known about the im...
ORGANISM(S): Rattus norvegicus 
2009-03-06 | E-GEOD-13414 | biostudies-arrayexpress
MetabolomicsMulti-platform metabolomics data from Ndufs4-/- skeletal muscles (part-II)
Not available
ORGANISM(S): Mus musculus 
ST001077 | MetabolomicsWorkbench
MetabolomicsMulti-platform metabolomics data from Ndufs4-/- skeletal muscles (part-IV)
Not available
ORGANISM(S): Mus musculus 
ST001085 | MetabolomicsWorkbench
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