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GenomicsMechanism of in vivo activation of the MutLgamma-Exo1 complex for meiotic crossover formation
Mechanism of in vivo activation of the MutLgamma-Exo1 complex for meiotic crossover formation
PRJNA549269 | ENA
GenomicsMechanism of in vivo activation of the MutLgamma-Exo1 complex for meiotic crossover formation
Programmed DNA double-strand breaks (DSBs) initiate meiotic recombination and their subsequent repair culminates in crossover (CO) formation. COs result from the asymmetric cleavage of double-Holliday junction (dHJ) intermediates, that requires the MutLγ complex together with a non-catalytic functio...
ORGANISM(S): Saccharomyces cerevisiae 
2019-12-01 | GSE132850 | GEO
UnknownGenetic dissection of crossover mutants defines discrete intermediates in mouse meiosis.
Not available
S-EPMC10469168 | biostudies-literature
ProteomicsPull-down of Mlh3-Flag from yeast meiotic cells and analysis of pulled-down partner proteins
Mlh3 internally tagged with Flag was pulled down from synchronous meiotic cells at t = 4 h in meiosis, in order to identify its interacting partners involved in meiotic crossover formation
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-11-06 | PXD014180 | Pride
Crossover Meiosis Recombination Mutlgamma 
ProteomicsPull-down of Exo1-TAP from yeast meiotic cells and analysis of phosphorylated residues
Exo1 tagged with the TAP sequence was pulled down from synchronous ndt80∆ meiotic cells after induction of the CDC5 kinase at t = 8 h 15 in meiosis (1 h 15 after CDC5 induction), in order to identify its phosphorylated residues
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-11-06 | PXD014185 | Pride
Crossover Meiosis Recombination Mutlgamma 
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