Myelination - OmicsDI

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Genomics (512)
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Organisms

Mus musculus (253)
Homo sapiens (60)
Rattus norvegicus (49)
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Oryctolagus cuniculus (2)
Macaca mulatta (2)
Trachemys scripta (1)
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Disease

Alzheimer's disease (3)
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Q Exactive (5)
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MS:1000031 (1)
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2010 (9)
2011 (8)
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2008 (3)
2004 (2)
2005 (1)
2006 (1)

CHEBI ID

CHEBI:156027 (1)
CHEBI:156019 (1)
CHEBI:156021 (1)
CHEBI:156016 (1)
CHEBI:136239 (1)
CHEBI:136257 (1)
CHEBI:136256 (1)
CHEBI:66865 (1)
CHEBI:72534 (1)
CHEBI:72533 (1)
CHEBI:141588 (1)
CHEBI:64519 (1)
CHEBI:64520 (1)
CHEBI:66857 (1)
CHEBI:64516 (1)
CHEBI:64517 (1)
CHEBI:66849 (1)
CHEBI:20392 (1)
CHEBI:18237 (1)
CHEBI:16811 (1)
CHEBI:28300 (1)
CHEBI:16708 (1)
CHEBI:506227 (1)
CHEBI:30838 (1)
CHEBI:17310 (1)
CHEBI:17750 (1)
CHEBI:73024 (1)
CHEBI:18183 (1)
CHEBI:16347 (1)
CHEBI:15354 (1)

Metabolite Name

PE 36:2 (2)
TG-d5 16:0_15:1_16:0 (1)
TG 18:3_18:3_18:2 (1)
TG 18:2_18:2_20:4 (1)
TG 17:1_18:2_18:2 (1)
TG 10:0_18:3_18:2 (1)
TG 10:0_18:2_18:2 (1)
TG 10:0_12:0_17:1 (1)
TG 10:0_10:0_18:2 (1)
SM-d9 18:1_24:1 (1)
SM-d9 18:1_22:1 (1)
SM-d9 18:1_20:1 (1)
SM d45:1 (1)
SM d44:2 (1)
SM d44:1 (1)
SM d42:1 (1)
SM d42:0 (1)
SM d41:1 (1)
SM d41:0 (1)
SM d40:1 (1)
SM d39:1 (1)
SM d37:1 (1)
SM d36:1 (1)
SM d33:1 (1)
SM d31:1 (1)
SM d28:1 (1)
PS-d5 17:0_22:4 (1)
PS-d5 17:0_20:3 (1)
PS-d5 17:0_18:1 (1)
PS-d5 17:0_16:1 (1)

First Public Date

2024 (74)
2025 (54)
2026 (52)
2023 (41)
2020 (40)
2022 (33)
2014 (31)
2018 (30)
2019 (21)
2021 (20)
2017 (18)
2016 (16)
2015 (7)
2013 (6)

Modification

4-tetrahydrothiazine-3-carboxylic acid (2)

Study type

Transcription profiling by array (44)
RNA-seq of coding RNA (16)
ChIP-seq (9)
Methylation profiling by high throughput sequencing (3)
Transcription profiling by SAGE (2)
ChIP-chip by tiling array (2)
Other (2)
RIP-chip by array (1)
Comparative genomic hybridization by array (1)
MicroRNA profiling by array (1)
Methylation profiling by array (1)

Release Date

2021 (261)
2025 (251)
2022 (249)
2023 (240)
2024 (203)
2019 (179)
2018 (164)
2020 (163)
2017 (148)
2016 (140)
2015 (97)
2014 (86)
2013 (47)
2012 (46)
2011 (36)
2010 (36)
2009 (34)
2026 (21)
2007 (21)
2008 (19)
2004 (10)
2005 (9)
2006 (9)
2003 (8)
2001 (4)
2002 (3)
2000 (3)
1999 (1)

Lab affiliation

Department of Chemical Sciences, University of Naples, Federico II, 80126, Naples, Italy (2)
UAB CCC MS Proteomics Facility (2)
Department of Neurology, Yale School of Medicine, Yale University, new haven CT, USA (2)
Neuroproteomics Group Department of Molecular Neurobiology Max Planck Institute for Multidisciplinary Sciences Hermann-Rein-Str. 3 37075 Goettingen Germany (2)
Assistant Professor of Neurosurgery, Stanford University (1)
Department of Molecular Sciences, Faculty of Science and Engineering, Macquarie University, Sydney, NSW, Australia (1)
Cambridge Institute of Therapeutic Immunology and Infectious Diseases, Department of Medicine, University of Cambridge, (1)
Center for Neuroscience Research Children's National Medical Center 111 Michigan Avenue N.W., M7631 Washington, DC 20010-2970 Phone: +1-202-476-4279 Fax: +1-202-476-4988 e-mail: MTorii@childrensnational.org (1)
Chiara Guerrera, IRHC, HDR Head of the Necker Proteomics Faculty of Medecine, University Paris Cité SFR Necker INSERM US24 160 rue de Vaugirard | 75015 Paris Tél. 01 40 61 54 6 (1)
Goethe University Frankfurt, Institute of molecular systems medicine (1)
Dept. Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Munich, Germany (1)
Department of Pharmacology, Physiology & Neuroscience School of Medicine University of South Carolina Columbia, South Carolina, 29209 USA (1)
Department of Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA (1)
PRISM U1192 Universite de Lille FRANCE (1)
The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine (1)
Swiss Federal Institute of Technology Zurich (ETH Zurich) Institute of Molecular Health Sciences (IMHS), Department of Biology (D-BIOL) (1)
Instituto de Investigação e Inovação em Saúde (i3S) - Universidade do Porto (1)
University Duisburg-Essen, Institute for Experimental Immunology and Imaging, Dept. of Immunodynamics (1)
Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum, 44801 Bochum, Germany; 44801 Bochum, Germany (1)
Jungers Center for Neurosciences Research Department of Neurology Oregon Health & Science University Portland, Oregon 97239, USA (1)
Department for Drug Design and Pharmacology, University of Copenhagen (1)
Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP) (1)
Laboratory of olecular oncology, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry (1)
Associate Professor, University of Maryland College Park, MD 20742 (1)
Proteomics Service CIC bioGUNE Bizkaia Tech. Park. Build. 800 Derio 48160 Spain (1)
School of Clinical Medicine, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, China, 750004. Ningxia Human Stem Cell Institute, General Hospital of Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, China, 750004. (1)
Head of Proteomics (1)

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Myelination of parvalbumin interneurons shapes the function of cortical sensory inhibitory circuits.

Not available

S-EPMC7555533 | biostudies-literature

Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination

The myelin sheaths that surround the thick axons of the peripheral nervous system are produced by the highly specialized Schwann cells. Differentiation of Schwann cells and myelination occur in discrete steps. Each of these requires coordinated expression of specific proteins in a precise sequence, ...

ORGANISM(S): Mus musculus

2010-12-01 | E-GEOD-22023 | biostudies-arrayexpress

Genome-wide mapping of Olig2 targets in primary oligodendrocytes

Myelination by oligodendrocytes in the central nervous system (CNS) is essential for proper brain function, yet the molecular determinants that control this process remain poorly understood. The basic helix-loop-helix transcription factors Olig1 and Olig2 promote myelination, whereas bone morphogene...

ORGANISM(S): Rattus norvegicus

2012-08-31 | E-GEOD-40506 | biostudies-arrayexpress

Expression data from Sip1 cKO and control mice spinal cord

ORGANISM(S): Mus musculus

2012-08-31 | E-GEOD-40510 | biostudies-arrayexpress

Identification of Myelin-gene Regulatory Factor as a Critical Transcriptional Regulator Required for CNS Myelination

The transcriptional control of CNS myelin gene expression is poorly understood. Here we identify gene model 98, which we have named Myelin-gene Regulatory Factor (MRF), as a transcriptional regulator required for CNS myelination. Within the CNS, MRF is specifically expressed by postmitotic oligodend...

ORGANISM(S): Mus musculus

2009-05-31 | E-GEOD-15303 | biostudies-arrayexpress

Genome-wide maps of Wnt effector Tcf7l2/Tcf4 occupancy in oligodendrocyte during CNS myelination

We performed genome-wide profiling of Tcf7l2 occupancy during oligodendrocyte differentiation and identified the key enzymes involved in cholesterol metabolism and essential for CNS myelination. Examination of Tcf7l2 chIP-seq in oligodendrocyte progenitor cell and 2 differentiation oligodendrocytes...

ORGANISM(S): Rattus norvegicus

2016-02-19 | E-GEOD-65119 | biostudies-arrayexpress

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

The progressive loss of CNS myelin in patients with multiple sclerosis (MS) has been proposed to result from the combined effects of damage to oligodendrocytes and failure of remyelination. A common feature of demyelinated lesions is the presence of oligodendrocyte precursors (OLPs) blocked at a pre...

ORGANISM(S): Mus musculus

2009-12-10 | E-GEOD-19403 | biostudies-arrayexpress

Expression Profile Analysis of Rat Motoneurons During Myelination

PRJNA552365 | ENA

A retroviral link to vertebrate myelination

PRJNA996536 | ENA

Histone Demethylase KDM6B Promotes Postnatal Oligodendrocyte Development and Cortical Myelination

PRJNA1455659 | ENA