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MetabolomicsResveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)
Resveratrol (RESV) is a plant polyphenol, which is thought to have beneficial metabolic effects in laboratory animals as well as in humans. Following oral administration, RESV is immediately catabolized, resulting in low bioavailability. This study compared RESV metabolites and their tissue distribu...
MTBLS127 | MetaboLights
MetabolomicsMetabolomic analysis of C2C12 myoblasts induced by the transcriptional factor FOXO1
Not available
ORGANISM(S): Mus musculus 
ST001178 | MetabolomicsWorkbench
TranscriptomicsThe transcriptomic signature of myostatin inhibitory influence on the differentiation of mouse C2C12 myoblasts
GDF8 (myostatin) is a unique cytokine strongly affecting the skeletal muscle phenotype in human and animals. The aim of the present study was to elucidate the molecular mechanism of myostatin influence on the differentiation of mouse C2C12 myoblasts, using the global-transcriptome analysis with the ...
ORGANISM(S): Mus musculus 
2014-07-23 | E-GEOD-59674 | biostudies-arrayexpress
ProteomicsComprehensive analysis of the proteome, phosphoproteome and N-linked sialylated glycoproteome of C2C12 myoblasts
C2C12 myoblast is a model that has been used extensively to study the process of skeletal muscle differentiation. Proteomics has advanced our understanding of skeletal muscle biology and the process of myogenesis. However, there is still no deep coverage of C2C12 myoblast proteome, which is importan...
ORGANISM(S): Mus musculus (Mouse) 
2020-11-27 | PXD011334 | Pride
Ptmome Mouse Skeletal myoblasts Proteome 
TranscriptomicsLoss of full-length dystrophin expression causes major cell-autonomous abnormalities in proliferating myoblasts
Duchenne muscular dystrophy (DMD) is a severely debilitating and incurable neuromuscular disease. Its conspicuous feature is the absence of dystrophin in myofibers and therefore most therapeutic approaches focus on some form of its re-expression there. However, increasing body of evidence points at ...
ORGANISM(S): Mus musculus 
2022-09-14 | E-MTAB-10322 | biostudies-arrayexpress
ProteomicsProteomic analysis of L6 myoblasts treated with C-terminal transgelin peptides
To investigate bioactivity of peptides identified in human plasma, we treated L6 myoblasts in vitro with a synthetic C-terminal peptide from TAGLN spanning amino acids 179-200, or a synthetic C-terminal peptide from TAGLN2 spanning amino acids 178-199 (1 µg/mL; 7 days), and compared the treatments t...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-11-21 | PXD007176 | Pride
Peptidomics Myoblasts Proteomics 
ProteomicsProteomic, phosphoproteomic and N-glycoproteomic analysis of small extracellular vesicles (sEVs) from C2C12 myoblasts
We conducted a comprehensive and integrated proteomic，phosphoproteomic, N-glycoproteomic analysis of the cargos in small extracellular vesicles (sEVs)-derived from C2C12 myoblasts.
ORGANISM(S): Mus Musculus 
2023-12-20 | PXD047974 |
TranscriptomicsRNA-seq comparison of immortalised myoblasts from dystrophic and WT mice
Pathophysiology of Duchenne Muscular Dystrophy (DMD) is still elusive. Although progressive damage to muscle fibres is a cause of muscle deterioration leading to premature death, there is a growing body of evidence indicating that the triggering effects of DMD mutation are present at the very early ...
ORGANISM(S): Mus musculus 
2019-10-02 | E-MTAB-7287 | biostudies-arrayexpress
GenomicsRNA-seq profiling of C/EBPβ-overexpressing myoblasts [differentiating myoblasts]
RNA-seq profiling of C/EBPβ-overexpressing myoblasts [differentiating myoblasts]
PRJNA638159 | ENA
GenomicsRNA-seq profiling of C/EBPβ-overexpressing myoblasts [proliferating myoblasts]
RNA-seq profiling of C/EBPβ-overexpressing myoblasts [proliferating myoblasts]
PRJNA638156 | ENA
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