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TranscriptomicsExpression Profiling of Early Myogenesis
This SuperSeries is composed of the following subset Series: GSE16992: Expression Profiling of Early Myogenesis - Affymetrix Dataset GSE17038: Expression Profiling of Early Myogenesis - Illumina Dataset Refer to individual Series
ORGANISM(S): Mus musculus 
2012-03-21 | E-GEOD-17039 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Early Myogenesis - Illumina Dataset
Myogenesis is a tightly controlled process involving the transcriptional activation and repression of thousands of genes. Although many components of the transcriptional network are known for the later phases of myogenesis, relatively little work has described the transcriptional landscape within th...
ORGANISM(S): Mus musculus 
2012-03-21 | E-GEOD-17038 | biostudies-arrayexpress
ProteomicsProteomic and phosphoproteomic of C2C12 myogenesis and MAPK inhibition
Myogenesis is governed by signalling networks whose regulations are tightly controlled in a time-dependent manner. While different protein kinases have been identified to regulate various aspects of myogenesis, knowledge on the global signalling networks and their downstream substrates during myogen...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-31 | PXD028713 | Pride
C2c12 Mapk Myogenesis 
TranscriptomicsExpression Profiling of Early Myogenesis - Affymetrix Dataset
Analysis of Early Myogenesis Reveals an Extensive Set of Transcriptional Regulators Whose Knock-down Can Inhibit Differentiation Myogenesis is a tightly controlled process involving the transcriptional activation and repression of thousands of genes. Although many components of the transcriptional n...
ORGANISM(S): Mus musculus 
2012-03-21 | E-GEOD-16992 | biostudies-arrayexpress
GenomicsGenetic and epigenetic determinants of neurogenesis and myogenesis [ChIP-seq]
The regulatory networks of differentiation programs have been partly characterized; however, the molecular mechanisms of lineage-specific gene regulation by highly similar transcription factors remain largely unknown. Here we compare the genome-wide binding and transcription profiles of NEUROD2-medi...
ORGANISM(S): Mus musculus 
2012-03-26 | E-GEOD-34906 | biostudies-arrayexpress
TranscriptomicsNovel RNA-binding activity of MYF5 enhances Ccnd1/Cyclin D1 mRNA translation during myogenesis
Skeletal muscle contains long multinucleated and contractile structures known as muscle fibers, which arise from the fusion of myoblasts into nucleated myotubes during myogenesis. The myogenic regulatory factor (MRF) MYF5 is the earliest to be expressed during myogenesis and functions as a transcri...
ORGANISM(S): Mus musculus 
2016-08-08 | E-GEOD-73704 | biostudies-arrayexpress
TranscriptomicsRNA-binding protein AUF1 promotes myogenesis by regulating MEF2C expression levels
The mammalian RNA-binding protein AUF1 (AU-binding factor 1, also known as heterogeneous nuclear ribonucleoprotein D, hnRNP D) binds to numerous mRNAs and influences their post-transcriptional fate. Given that many AUF1 target mRNAs encode muscle-specific factors, we investigated the function of AU...
ORGANISM(S): Mus musculus 
2014-12-22 | E-GEOD-58259 | biostudies-arrayexpress
TranscriptomicsGenetic and epigenetic determinants of neurogenesis and myogenesis [expression profiling]
The regulatory networks of differentiation programs have been partly characterized; however, the molecular mechanisms of lineage-specific gene regulation by highly similar transcription factors remain largely unknown. Here we compare the genome-wide binding and transcription profiles of NEUROD2-medi...
ORGANISM(S): Mus musculus 
2012-03-26 | E-GEOD-34907 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C2C12 cells cultured either in 20% serum (undifferentiated) or in 2% horse serum (differentiated) to detail the global changes of gene expression in lamins and nuclear envelope assoicated proteins during myogenesis
During muscle differentiation, myogenesis sepcific genes are differentially regulated, including Lamins that function at least in maintenance of nuclear architecture and regulation of gene expression. We used microarrays to detail the global changes of gene expression in lamins and nuclear envelope ...
ORGANISM(S): Mus musculus 
2007-11-22 | E-GEOD-4694 | biostudies-arrayexpress
ProteomicsProteomic and glycoproteomic analysis of myogenesis
The majority of cell surface and secreted proteins are modified by glycans and this glycosylation process plays an important role in the development of multicellular organisms. These glycan modifications enable communication between cells and the extracellular matrix via interactions with specific g...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-15 | PXD019372 | Pride
Glycoproteomics N-linked glycosylation Myogenesis 
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