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RNA-seqence analysis of MYPT1 target genes in subcutaneous white adipoce tissue cells.
Protein kinase A promotes beige adipogenesis downstream from β-adrenergic receptor signaling by phosphorylating proteins, including histone H3 lysine 9 (H3K9) demethylase JMJD1A. To ensure homeostasis, this process needs to be reversible however, this step is not well understood. We show that myosin...
ORGANISM(S): Mus musculus 
2022-09-01 | GSE202504 | GEO
RBM25 drives hepatocellular carcinoma progression by regulating oncogenic splicing of MYPT1 and translation of YAP
Deregulated splicing factors lead to aberrant alternative splicing (AS), which plays a critical role in tumorigenesis and cancer progression. However, pinpointing the targets and understanding the inherent mechanisms of AS in Hepatocellular Carcinoma (HCC) tumorigenesis remains a complex task. Here,...
ORGANISM(S): Homo sapiens 
2026-09-21 | GSE284351 | GEO
To comprehensively understand the mechanism by which MYPT1 modulates the phenotypic switching of VSMCs after ischemic stroke, the proteins of cortical small vessel from MYPT1SMKO and WT mice subjected to MCAO or sham group were collected for proteomic screening.
ORGANISM(S): Mus musculus (Mouse) 
2021-08-21 | PXD027869 | Pride
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