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IP-MS experiments to identify interacting proteins of Toxoplasma MYR1.
ORGANISM(S): Homo sapiens (Human) Toxoplasma gondii RH 
2020-02-20 | PXD016383 | Pride
MYR1-dependent effectors are the major drivers of a host cell’s early response to Toxoplasma including counteracting MYR1-independent effects
The intracellular parasite Toxoplasma gondii uses a diverse repertoire of effector molecules to manipulate its host cell. The first effectors to be introduced into the host cell derive from rhoptries (ROPs) and are secreted exclusively during invasion. Once the parasite has established a parasitopho...
ORGANISM(S): Homo sapiens 
2018-01-31 | GSE109830 | GEO
The purpose of these data is to determine if the impact bradyzoites have on the host transcripton is dependent on the export of parasite effector proteins via Myr1. We found that the expression of 3,068 host genes (~42%) were dependent on Myr1. A further 4,312 were altered in the same direction when...
ORGANISM(S): Homo sapiens Toxoplasma gondii 
2020-01-15 | GSE125120 | GEO
RNA sequencing of host transcriptome of human foreskin fibroblast cells infected with Toxoplasma gondii bradyzoites, with and without myr1 (myc regulation 1)
Toxoplasma controls host cyclin E expression through the use of a novel MYR1-dependent effector protein, HCE1
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