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TranscriptomicsExpression profiling in primary embryonic fibroblasts deficient for the N-terminal truncation of Lats1
Lats1 and Lats2 are the mediators of the Hippo pathway that regulates tissue growth and proliferation. Lats1 and Lats2 kinases share 85% sequence identity in the kinase domain. However, their non-kinase regions at the N-terminus are distinct except for Lats conserved domain 1 (LCD1) and LCD2, sugges...
ORGANISM(S): Mus musculus 
2012-12-17 | E-GEOD-37871 | biostudies-arrayexpress
ProteomicsPositional proteomics reveals differences in N-terminal proteoform stability.
To understand the impact of alternative translation initiation on a proteome, we performed the first large-scale study of protein turnover rates in which we distinguish between N-terminal proteoforms pointing to translation initiation events. Using pulsed SILAC combined with N-terminal COFRADIC we m...
ORGANISM(S): Homo sapiens (Human) 
2013-03-14 | PXD002091 | Pride
Nt-acetylation Protein stability Alternative translation initiation Initiator methionine processing Protein turnover N-terminal proteoform Human N-terminal cofradic 
ProteomicsPositional proteomics reveals differences in N-terminal proteoform stability.
To understand the impact of alternative translation initiation on a proteome, we performed the first large-scale study of protein turnover rates in which we distinguish between N-terminal proteoforms pointing to translation initiation events. Using pulsed SILAC combined with N-terminal COFRADIC we m...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-03-13 | MSV000083565 | MassIVE
UnknownMacrophage-specific N-terminal truncation of Plin2 limits the size of lipid droplets.
Not available
S-EPMC12921128 | biostudies-literature
ProteomicsN-terminal VP1 truncation favor T=1 norovirus-like particles
Noroviruses cause immense sporadic gastroenteritis outbreaks worldwide. Upcoming genotypes, which are divided based on VP1 sequence, further enhance this public thread regularly. Self-assembling properties of the human norovirus major capsid protein VP1 are crucial for using virus-like particles (VL...
ORGANISM(S): Norovirus 
2021-01-11 | PXD023182 | Pride
Capsid assembly Norovirus Vp1 truncation 
UnknownN-terminal truncation of PhaCBP-M-CPF4 and its effect on PHA production.
Not available
S-EPMC10867992 | biostudies-literature
UnknownSENP2-based N-terminal truncation of α-synuclein in Lewy pathology propagation.
Not available
S-EPMC11869972 | biostudies-literature
UnknownDefining essential charged residues in fibril formation of a lysosomal derived N-terminal α-synuclein truncation.
Not available
S-EPMC12019160 | biostudies-literature
UnknownThe effect of N-terminal truncation on double-dimer assembly of goose delta-crystallin.
Not available
S-EPMC1316294 | biostudies-literature
UnknownImprovement of thermostability and catalytic efficiency of xylanase from Myceliophthora thermophilar by N-terminal and C-terminal truncation.
Not available
S-EPMC11039872 | biostudies-literature
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