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UnknownExternal validation and update of a prognostic model to predict mortality in hospitalized adults with RSV: A retrospective Dutch cohort study.
Respiratory syncytial virus (RSV) causes significant mortality in hospitalized adults. Prediction of poor outcomes improves targeted management and clinical outcomes. We externally validated and updated existing models to predict poor outcome in hospitalized RSV-infected adults. In this single cente...
S-EPMC6851775 | biostudies-literature
UnknownPrognostic models versus single risk factor approach in first-trimester selective screening for gestational diabetes mellitus: a prospective population-based multicentre cohort study.

Objectives

To evaluate whether (1) first-trimester prognostic models for gestational diabetes mellitus (GDM) outperform the currently used single risk factor approach, and (2) a first-trimester random venous glucose measurement improves model performance.

Design

Prospective population...
S-EPMC7891327 | biostudies-literature
UnknownReducing Test Utilization in Hospital Settings: A Narrative Review.

Background

Studies addressing the appropriateness of laboratory testing have revealed approximately 20% overutilization. We conducted a narrative review to (1) describe current interventions aimed at reducing unnecessary laboratory testing, specifically in hospital settings, and (2) provide ...
S-EPMC5973913 | biostudies-literature
UnknownStudy protocol for a randomised trial for atosiban versus placebo in threatened preterm birth: the APOSTEL 8 study.

Introduction

Preterm birth complicates >15 million pregnancies annually worldwide. In many countries, women who present with signs of preterm labour are treated with tocolytics for 48 hours. Although this delays birth, it has never been shown to improve neonatal outcome. In 2015, the WHO sta...
S-EPMC6887072 | biostudies-literature
UnknownEffects of tocolysis with nifedipine or atosiban on child outcome: follow-up of the APOSTEL III trial.

Objective

To compare the long-term effects of tocolysis with nifedipine or atosiban on child outcome at age 2.5-5.5 years.

Design

The APOSTEL III trial was a multicentre randomised controlled trial that compared tocolysis with nifedipine or atosiban in 503 women with threatened preter...
S-EPMC7384124 | biostudies-literature
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