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ProteomicsCRK2-mediated control of ROS production by phosphorylation of the RBOHD C-terminus in Arabidopsis
Reactive oxygen species (ROS) are important messengers in eukaryotic organisms. Extracellular ROS production by NADPH oxidases in plants is triggered by receptor-like protein kinase (RLK)-dependent signaling networks. This ROS production is tightly controlled by multiple mechanisms including phospho...
ORGANISM(S): Arabidopsis Thaliana 
2020-03-27 | PXD013525 | panorama
TranscriptomicsThe plasma membrane NADPH oxidase OsRbohA plays a crucial role in developmental regulation and drought-stress response in rice
Plasma membrane NADPH oxidases (NOXs) are major producers of reactive oxygen species (ROS) in plant cells under normal growth and stress conditions. Rice NOXs have multiple homologs but their functional mechanisms are largely unknown. We used microarrays to detail the global gene expression profiles...
ORGANISM(S): Oryza sativa Japonica Group 
2015-12-31 | E-GEOD-54466 | biostudies-arrayexpress
ProteomicsSILAC-based quantitative Nox4-Co-immunoprecipitation
Within the family of NADPH oxidases, Nox4 is unique as it is predominantly localized in the endoplasmic reticulum, has constitutive activity and generates H2O2. We hypothesize that these features are consequences of a so far unidentified Nox4-interacting protein. Interacting proteins were screened ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080772 | MassIVE
TranscriptomicsTranscriptome analysis of a Sordaria macrospora nox1 mutant
The Sordaria macrospora nox1 mutant has a block in sexual development at the stage of protoperithecia formation, and therefore is sterile. The aim of this study was to determine the transcriptome of microdissected protoperithecia from the mutant, as well as the transcriptomes of total RNA from the m...
ORGANISM(S): Sordaria macrospora 
2014-03-10 | E-GEOD-49363 | biostudies-arrayexpress
TranscriptomicsGenes rapidly regulated by Ara-C and DNR treatment of HL-60 AML cells and role of NADPH-oxidase derived ROS in DNR-induced gene expression
Daunorubicin (DNR) and Cytarabin (Ara-C) are the main chemotherapeutic drugs used for Acute Myeloid Leukemias (AML) treatment. However, their mode of action is not well understood. To decipher if these drug would induce rapid transcriptional reprogramming, we treated HL-60 AML cell line with DNR or ...
ORGANISM(S): Homo sapiens 
2017-12-31 | E-MTAB-4895 | biostudies-arrayexpress
ProteomicsEROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling.
The phagocyte NADPH oxidase is critical for host defence, and EROS (Essential for Reactive Oxygen Species) protein is indispensable for expression of its gp91phox-p22phox heterodimer. EROS deficiency in humans is a recently described cause of chronic granulomatous disease (CGD), but its mechanism of...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-30 | PXD025149 | Pride
Nox family Inflammasome Nadph oxidase Ost complex Chaperone T cells P2x receptor Er 
UnknownNeurospora crassa NADPH Oxidase NOX-1 Is Localized in the Vacuolar System and the Plasma Membrane.
Not available
S-EPMC6702951 | biostudies-literature
UnknownNADPH Oxidases (NOX): An Overview from Discovery, Molecular Mechanisms to Physiology and Pathology.
Not available
S-EPMC8228183 | biostudies-literature
UnknownExpression of NADPH oxidase (NOX) 5 in rabbit corneal stromal cells.
Not available
S-EPMC3325249 | biostudies-literature
GenomicsPhagocytosis-related NADPH oxidase 2 subunit gp91phox contributes to neurodegeneration after repeated systemic challenge with lipopolysaccharides
Phagocytosis-related NADPH oxidase 2 subunit gp91phox contributes to neurodegeneration after repeated systemic challenge with lipopolysaccharides
PRJNA642158 | ENA
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